Zyrtec and Spectazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Spectazole (econazole nitrate). Common drug interactions include bradycardia among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Spectazole. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Spectazole?

Spectazole has active ingredients of econazole nitrate. eHealthMe is studying from 248 Spectazole users. Check the latest studies of Spectazole.

On Jul, 09, 2026

15 people who take Zyrtec and Spectazole together, and have interactions are studied.

Zyrtec and Spectazole drug interactions.

What are the common drug interactions of Zyrtec and Spectazole, by gender? *:

female:

Bradycardia (abnormally slow heart action)
Dehydration (dryness resulting from the removal of water)
Depression
Diarrhoea
Hypokalaemia (low potassium)
Syncope (loss of consciousness with an inability to maintain postural tone)
Anaemia (lack of blood)
Arthropathy
Cardiac disorder
Cardiac failure congestive

male:

Back pain
Chronic kidney disease
Hyperlipidaemia (presence of excess lipids in the blood)
Insulin-requiring type 2 diabetes mellitus
Splenomegaly (enlargement of spleen)
Thrombocytopenia (decrease of platelets in blood)
Gait disturbance
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in extremity
Renal failure (kidney dysfunction)

What are the common drug interactions of Zyrtec and Spectazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Colitis ulcerative (inflammation of colon with ulcer)
Depression
Emotional distress
Inflammatory bowel disease
Irritable bowel syndrome
Polyp
Rash
Sinus congestion (blockage of sinus)
Suicidal ideation

20-29:

n/a

30-39:

Abdominal distension
Abdominal pain
Abdominal pain upper
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Constipation
Drug maladministration
Fatigue (feeling of tiredness)
Listless (lack of interest, energy, or spirit)
Loose stools
Pallor

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Back pain
Gait disturbance
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in extremity
Nephropathy (damage to or disease of a kidney)

50-59:

Bradycardia (abnormally slow heart action)
Dehydration (dryness resulting from the removal of water)
Hypokalaemia (low potassium)
Syncope (loss of consciousness with an inability to maintain postural tone)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Diarrhoea

60+:

Anaemia (lack of blood)
Arthropathy
Dyspnoea (difficult or laboured respiration)
Gastric ulcer (stomach ulcer)
Gastritis (inflammation of stomach)
Gastrointestinal ulcer haemorrhage (bleeding ulcer of digestive system)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatitis c
Hyperbilirubinaemia (excess of bilirubin in the blood)
Melaena (the passage of black, tarry stools)

What are the existing conditions these people have? *

Breast Cancer Metastatic: 4 people, 26.67%
Depression: 4 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
Pain: 3 people, 20.00%
High Blood Pressure: 3 people, 20.00%
Abdominal Discomfort: 2 people, 13.33%
High Blood Cholesterol: 2 people, 13.33%
Oedema (fluid collection in tissue): 2 people, 13.33%
Eye Infection: 2 people, 13.33%
Hypersensitivity: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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