Urso 250 and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Urso 250 (ursodiol) and Acetaminophen (acetaminophen). Common drug interactions include ascites among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Urso 250 and Acetaminophen. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Urso 250?

Urso 250 has active ingredients of ursodiol. eHealthMe is studying from 5,080 Urso 250 users. Check the latest studies of Urso 250.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.



On Jul, 09, 2026

84 people who take Urso 250 and Acetaminophen together, and have interactions are studied.

Urso 250 and Acetaminophen drug interactions.

What are the common drug interactions of Urso 250 and Acetaminophen, by gender? *:

female:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Cellulitis (infection under the skin)
  4. Drug eruption (adverse drug reaction of the skin)
  5. Hepatitis c
  6. Histiocytosis haematophagic
  7. Infection
  8. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  9. Pyrexia (fever)
  10. Renal disorder (kidney disease)

male:

  1. Pyrexia (fever)
  2. Rash
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. C-reactive protein increased
  5. Depression
  6. Renal disorder (kidney disease)
  7. Infection
  8. Interstitial lung disease
  9. Pneumonia
  10. Disseminated intravascular coagulation (systemic activation of blood coagulation)

What are the common drug interactions of Urso 250 and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Respiratory distress (difficulty in breathing)

10-19:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  3. Hepatic vein occlusion (blockage of the hepatic vein)
  4. Abulia (lack of will or initiative)
  5. Arrhythmia (irregular heartbeat)
  6. Blindness cortical
  7. Cardiac failure
  8. Dehydration (dryness resulting from the removal of water)
  9. Encephalitis (inflammation of the brain)
  10. Haematuria (presence of blood in urine)

20-29:

  1. Pyrexia (fever)

30-39:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Blood culture positive
  3. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  4. Cellulitis (infection under the skin)
  5. Cytomegalovirus infection
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  8. Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
  9. General physical health deterioration (weak health status)
  10. Immunodeficiency

40-49:

  1. Multi-organ failure (multisystem organ failure)
  2. Pyrexia (fever)
  3. Platelet count decreased
  4. Anaemia (lack of blood)
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  7. Cellulitis (infection under the skin)
  8. Drug eruption (adverse drug reaction of the skin)
  9. Hepatitis c
  10. Histiocytosis haematophagic

50-59:

  1. Neoplasm malignant (cancer tumour)
  2. Neoplasm progression (growth of tumour)
  3. Pancreatitis acute (sudden inflammation of pancreas)
  4. Platelet count decreased
  5. Anaemia (lack of blood)
  6. Hepatic failure (liver failure)
  7. Pyrexia (fever)
  8. Renal failure (kidney dysfunction)
  9. Renal impairment (severely reduced kidney function)
  10. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)

60+:

  1. Pyrexia (fever)
  2. Diarrhoea
  3. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  4. Platelet count decreased
  5. Decreased appetite
  6. Hepatic failure (liver failure)
  7. Infection
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Drug ineffective
  10. Hypersensitivity

What are the existing conditions these people have? *

  1. Hepatitis C: 25 people, 29.76%
  2. Insomnia (sleeplessness): 12 people, 14.29%
  3. High Blood Pressure: 10 people, 11.90%
  4. Hepatic Neoplasm Malignant (liver cancer): 9 people, 10.71%
  5. Fever: 7 people, 8.33%
  6. Immunodeficiency Disorders: 6 people, 7.14%
  7. Nasopharyngeal Cancer (cancer of nasopharynx): 5 people, 5.95%
  8. Breast Cancer Recurrent: 5 people, 5.95%

* Approximation only. Some reports may have incomplete information.

Do you take Urso 250 and Acetaminophen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Urso 250 and Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Urso 250:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Urso 250 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol and acetaminophen (the active ingredients of Urso 250 and Acetaminophen, respectively), and Urso 250 and Acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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