Levaquin and Aggrenox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Levaquin (levofloxacin) and Aggrenox (aspirin; dipyridamole). Common drug interactions include dyspnoea among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Levaquin and Aggrenox. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.
What is Levaquin?
Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.
What is Aggrenox?
Aggrenox has active ingredients of aspirin; dipyridamole. It is often used in stroke. eHealthMe is studying from 7,654 Aggrenox users. Check the latest studies of Aggrenox.
90 people who take Levaquin and Aggrenox together, and have interactions are studied.

What are the common drug interactions of Levaquin and Aggrenox, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Hypertension (high blood pressure)
- Pain
- Renal failure chronic (long lasting kidney dysfunction)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Renal failure (kidney dysfunction)
- Cardiac failure congestive
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Impaired healing
- Injury
male:
- Pain
- Anxiety
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cerebellar infarction (impaired blood circulation to cerebellum)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Confusional state
- Urinary tract infection
- Abdominal discomfort
- Back pain
What are the common drug interactions of Levaquin and Aggrenox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Chronic kidney disease
- Emotional distress
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
50-59:
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cerebellar infarction (impaired blood circulation to cerebellum)
- Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
- Diarrhoea
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Dizziness
- Fall
- Gastritis (inflammation of stomach)
60+:
- Anxiety
- Pain
- Asthenia (weakness)
- Depression
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Oesophagitis (inflammation of oesophagus)
- Osteonecrosis of jaw (death of bone of jaw)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Herpes zoster
- Oedema peripheral (superficial swelling)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 16 people, 17.78%
- Pain: 14 people, 15.56%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 15.56%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 13 people, 14.44%
- High Blood Pressure: 13 people, 14.44%
- Cardiac Disorder: 11 people, 12.22%
- Stress And Anxiety: 10 people, 11.11%
- High Blood Cholesterol: 10 people, 11.11%
- Urinary Tract Infection: 10 people, 11.11%
- Infection: 9 people, 10.00%
* Approximation only. Some reports may have incomplete information.
Do you take Levaquin and Aggrenox?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Levaquin and Aggrenox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Levaquin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aggrenox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levaquin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aggrenox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on levofloxacin and aspirin; dipyridamole (the active ingredients of Levaquin and Aggrenox, respectively), and Levaquin and Aggrenox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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