Levaquin and Nicotrol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Levaquin (levofloxacin) and Nicotrol (nicotine). Common drug interactions include renal failure among females and abasia among males.
The phase IV clinical study analyzes what interactions people have when they take Levaquin and Nicotrol. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Levaquin?
Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.
What is Nicotrol?
Nicotrol has active ingredients of nicotine. eHealthMe is studying from 4,104 Nicotrol users. Check the latest studies of Nicotrol.
19 people who take Levaquin and Nicotrol together, and have interactions are studied.

What are the common drug interactions of Levaquin and Nicotrol, by gender? *:
female:
- Renal failure (kidney dysfunction)
- Intervertebral disc degeneration (spinal disc degeneration)
- Intervertebral disc protrusion (spinal disc protrusion)
- Intestinal polyp (small growths in the bowel with the potential for further growth)
- Irritability
- Nephropathy (damage to or disease of a kidney)
- Type 2 diabetes mellitus
- Blood cholesterol increased
- Gallbladder operation
- Sensation of foreign body
male:
- Abasia (inability to walk)
- Arthralgia (joint pain)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Femur fracture
- Pain in extremity
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Cardiac disorder
- Chronic kidney disease
- Renal failure (kidney dysfunction)
What are the common drug interactions of Levaquin and Nicotrol, by age (0-1 to 60+)? *:
0-1:
- Blood cholesterol increased
- Gallbladder operation
- Sensation of foreign body
- Type 2 diabetes mellitus
2-9:
- Abasia (inability to walk)
- Arthralgia (joint pain)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Femur fracture
- Pain in extremity
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Cardiac disorder
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Vasculitic rash (inflammation of a blood vessel or blood vessels with rashes under the skin)
- Cardiac failure congestive
- Diabetic coma
- Diabetic complication
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Neuropathy peripheral (surface nerve damage)
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
- Unresponsive to stimuli
50-59:
- Chronic kidney disease
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Leukoplakia (white and gray patches inside the mouth)
- Renal failure (kidney dysfunction)
- Vocal cord polyp
- Abdominal pain
- Asthma
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Cardiovascular disorder (heart diseases)
- Cholecystitis (infection of gallbladder)
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Nephropathy (damage to or disease of a kidney)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 52.63%
- Pain: 8 people, 42.11%
- Depression: 7 people, 36.84%
- Nausea (feeling of having an urge to vomit): 7 people, 36.84%
- High Blood Pressure: 6 people, 31.58%
- Infection: 6 people, 31.58%
- Diarrhea: 5 people, 26.32%
- Sleep Disorder: 4 people, 21.05%
- Insomnia (sleeplessness): 4 people, 21.05%
- Quit Smoking: 4 people, 21.05%
* Approximation only. Some reports may have incomplete information.
Do you take Levaquin and Nicotrol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Levaquin and Nicotrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Levaquin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nicotrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levaquin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nicotrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on levofloxacin and nicotine (the active ingredients of Levaquin and Nicotrol, respectively), and Levaquin and Nicotrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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