Levothyroxine sodium and Pegintron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levothyroxine sodium (levothyroxine sodium) and Pegintron (peginterferon alfa-2b). Common drug interactions include transaminases increased among females and neutrophil count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Levothyroxine sodium and Pegintron. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,814 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

What is Pegintron?

Pegintron has active ingredients of peginterferon alfa-2b. It is often used in hepatitis c. eHealthMe is studying from 10,326 Pegintron users. Check the latest studies of Pegintron.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

58 people who take Levothyroxine sodium and Pegintron together, and have interactions are studied.

Levothyroxine sodium and Pegintron drug interactions.

What are the common drug interactions of Levothyroxine Sodium and Pegintron, by gender? *:

female:

Transaminases increased
Chills (felling of cold)
Feeling hot
Mood altered (changes in mood)
White blood cell count decreased
Abdominal pain
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anxiety
Full blood count decreased
Influenza like illness

male:

Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Decreased appetite
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Vomiting
Chills (felling of cold)
Weight decreased
White blood cell count decreased
Anaemia (lack of blood)
Depression
Dizziness

What are the common drug interactions of Levothyroxine Sodium and Pegintron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Haemoglobin decreased
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)

30-39:

n/a

40-49:

Cardiac death
Abdominal pain
Chest discomfort
Cold sweat
Cough
Dysphonia (speech disorder attributable to a disorder of phonation)
Face oedema (swelling of face)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Injection site pruritus (severe itching at injection site)

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Psychomotor hyperactivity (feelings of extreme restlessness)
Radical hysterectomy
Weight increased
Ankle fracture
Balance disorder
Fall
Feeling hot

60+:

Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Decreased appetite
Pyrexia (fever)
Vomiting
Weight decreased
Chills (felling of cold)
Diarrhoea
Platelet count decreased
Asthenia (weakness)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 6.90%
Diabetes: 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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