Levoxyl and Levemir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levoxyl (levothyroxine sodium) and Levemir (insulin detemir recombinant). Common drug interactions include aspartate aminotransferase increased among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Levoxyl and Levemir. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,178 Levoxyl users. Check the latest studies of Levoxyl.

What is Levemir?

Levemir has active ingredients of insulin detemir recombinant. It is often used in diabetes. eHealthMe is studying from 13,850 Levemir users. Check the latest studies of Levemir.

On Jul, 27, 2026

51 people who take Levoxyl and Levemir together, and have interactions are studied.

What are the common drug interactions of Levoxyl and Levemir, by gender? *:

female:

Aspartate aminotransferase increased
Asthenia (weakness)
Back pain
Breath odour
Clostridium test positive
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Dysarthria (speech disorder)
Dysgeusia (disorder of the sense of taste)
Dysphonia (speech disorder attributable to a disorder of phonation)

male:

Asthma
Blood glucose decreased
Weight decreased
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Acute respiratory failure
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cellulitis (infection under the skin)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)

What are the common drug interactions of Levoxyl and Levemir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Sinusitis (inflammation of sinus)
Blood glucose increased
Chest pain
Dehydration (dryness resulting from the removal of water)
Ear infection
Fungal infection
Heart rate increased

30-39:

Dyspnoea (difficult or laboured respiration)
Asthma
Chest pain
Fatigue (feeling of tiredness)
Heart rate increased
Injection site swelling
Intervertebral disc protrusion (spinal disc protrusion)

40-49:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Blood glucose fluctuation
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Renal impairment (severely reduced kidney function)
Weight increased
Blood glucose increased
Drug ineffective
Dysarthria (speech disorder)
Faecal incontinence (a lack of control over passing stool)
Gait disturbance

50-59:

Gallbladder disorder
Headache (pain in head)
Large intestine perforation (hole in large intestine)
Pancreatitis (inflammation of pancreas)
Swelling face
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal pain
Asthma
Bile duct stone
Blood glucose decreased

60+:

Gait disturbance
Dizziness
Nausea (feeling of having an urge to vomit)
Weight decreased
Back pain
Drug ineffective
Dry skin
Hypotension (abnormally low blood pressure)
Injection site pain
Pain in extremity

What are the existing conditions these people have? *

Type 1 Diabetes: 8 people, 15.69%
Type 2 Diabetes: 7 people, 13.73%
Neuropathy Peripheral (surface nerve damage): 7 people, 13.73%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.80%
Asthma: 5 people, 9.80%
Migraine (headache): 4 people, 7.84%
High Blood Cholesterol: 4 people, 7.84%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 5.88%
High Blood Pressure: 3 people, 5.88%
Depression: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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