Venclexta and Pioglitazone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Venclexta (venetoclax) and Pioglitazone (pioglitazone hydrochloride). Common drug interactions include asthenia among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Venclexta and Pioglitazone. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Venclexta?

Venclexta has active ingredients of venetoclax. eHealthMe is studying from 31,425 Venclexta users. Check the latest studies of Venclexta.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.



On Jul, 27, 2026

34 people who take Venclexta and Pioglitazone together, and have interactions are studied.

Venclexta and Pioglitazone drug interactions.

What are the common drug interactions of Venclexta and Pioglitazone, by gender? *:

female:

  1. Asthenia (weakness)
  2. Body temperature increased
  3. Carbon dioxide increased
  4. Infection
  5. Pulmonary oedema (fluid accumulation in the lungs)
  6. Granulocyte count decreased
  7. Herpes zoster
  8. High density lipoprotein decreased
  9. Localised infection (infection at the single location)
  10. Myalgia (muscle pain)

male:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Vomiting
  3. Death
  4. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Haemorrhage intracranial (bleeding within the skull)
  7. Pain
  8. Pleural effusion (water on the lungs)
  9. Pneumonia fungal
  10. Cellulitis (infection under the skin)

What are the common drug interactions of Venclexta and Pioglitazone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Death
  2. Granulocyte count decreased
  3. High density lipoprotein decreased
  4. Myalgia (muscle pain)
  5. Myelosuppression (a decrease in the production of blood cells)
  6. White blood cell count decreased

60+:

  1. Vomiting
  2. Nausea (feeling of having an urge to vomit)
  3. B-cell lymphoma (blood cancer affecting b cells)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
  6. Vagus nerve paralysis
  7. Asthenia (weakness)
  8. Dyspnoea (difficult or laboured respiration)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Chest pain

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 41.18%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 11 people, 32.35%
  3. Neuropathy Peripheral (surface nerve damage): 3 people, 8.82%
  4. Type 2 Diabetes: 2 people, 5.88%
  5. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.88%
  6. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 5.88%
  7. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 5.88%
  8. Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 2 people, 5.88%
  9. Hypotension (abnormally low blood pressure): 2 people, 5.88%
  10. High Blood Pressure: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Venclexta and Pioglitazone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Venclexta and Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Venclexta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pioglitazone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on venetoclax and pioglitazone hydrochloride (the active ingredients of Venclexta and Pioglitazone, respectively), and Venclexta and Pioglitazone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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