Levoxyl and Thalomid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levoxyl (levothyroxine sodium) and Thalomid (thalidomide). Common drug interactions include periodic limb movement disorder among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Levoxyl and Thalomid. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,178 Levoxyl users. Check the latest studies of Levoxyl.

What is Thalomid?

Thalomid has active ingredients of thalidomide. It is often used in multiple myeloma. eHealthMe is studying from 38,099 Thalomid users. Check the latest studies of Thalomid.



On Jul, 18, 2026

71 people who take Levoxyl and Thalomid together, and have interactions are studied.

Levoxyl and Thalomid drug interactions.

What are the common drug interactions of Levoxyl and Thalomid, by gender? *:

female:

  1. Periodic limb movement disorder
  2. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  3. Spinal disorder (disease of spine a back bone)
  4. Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
  5. Ventricular extrasystoles (premature cardiac contraction)
  6. Muscular weakness (muscle weakness)
  7. Anaemia (lack of blood)
  8. Aphasia (damage to the parts of the brain that control language)
  9. Asthma
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

  1. Anaemia (lack of blood)
  2. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  3. Blood albumin decreased
  4. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  5. Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
  6. Constipation
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Defaecation urgency (a sudden compelling urge to defecate)
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Diarrhoea

What are the common drug interactions of Levoxyl and Thalomid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Body temperature decreased
  2. Disease progression
  3. Oedema peripheral (superficial swelling)
  4. Skin discolouration (change of skin colour)
  5. Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Bacteraemia (presence of bacteria in the blood)
  3. Blood amylase increased
  4. Blood cholesterol increased
  5. Blood creatine phosphokinase mb increased
  6. Blood creatinine increased
  7. Blood thyroid stimulating hormone increased
  8. Blood triglycerides increased
  9. Cellulitis (infection under the skin)
  10. Coma (state of unconsciousness lasting more than six hours)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Neuropathy (damage to nerves)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Platelet count decreased
  6. Pyrexia (fever)
  7. Rouleaux formation (when red blood cells stack on to each other due to an abnormal shape)
  8. Troponin increased
  9. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  10. Alopecia (absence of hair from areas of the body)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  4. Swelling
  5. Aphthous stomatitis (mouth ulcer)
  6. Back pain
  7. Depressed mood
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  9. Haematemesis (vomiting of blood)
  10. Hot flush (sudden feelings of heat)

What are the existing conditions these people have? *

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Levoxyl and Thalomid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levoxyl and Thalomid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levoxyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Thalomid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levoxyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Thalomid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium and thalidomide (the active ingredients of Levoxyl and Thalomid, respectively), and Levoxyl and Thalomid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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