Lexapro and Alli drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Alli (orlistat). Common drug interactions include abdominal pain among females and blood glucose decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Alli. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Alli?

Alli has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 22,818 Alli users. Check the latest studies of Alli.



On Jul, 26, 2026

44 people who take Lexapro and Alli together, and have interactions are studied.

Lexapro and Alli drug interactions.

What are the common drug interactions of Lexapro and Alli, by gender? *:

female:

  1. Abdominal pain
  2. Hypersomnia (excessive daytime sleepiness (eds))
  3. Anal haemorrhage
  4. Balance disorder
  5. Flatulence (flatus expelled through the anus)
  6. Gallbladder disorder
  7. Haematochezia (passage of stools containing blood)
  8. Loss of consciousness
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pruritus (severe itching of the skin)

male:

  1. Blood glucose decreased
  2. Hypoglycaemia (deficiency of glucose in the bloodstream)
  3. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  4. Type 2 diabetes mellitus

What are the common drug interactions of Lexapro and Alli, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Haematochezia (passage of stools containing blood)
  3. Rectal haemorrhage (bleeding from anus)
  4. Speech disorder
  5. Thrombosis (formation of a blood clot inside a blood vessel)
  6. Thyroiditis (inflammation of thyroid gland)
  7. Weight increased
  8. Dizziness
  9. Flatulence (flatus expelled through the anus)
  10. Loss of consciousness

30-39:

  1. Balance disorder
  2. Diarrhoea
  3. Dizziness
  4. Fall
  5. Haemoglobin increased
  6. Hypotension (abnormally low blood pressure)
  7. Loss of consciousness
  8. Anal haemorrhage
  9. Blood bilirubin increased
  10. Effusion (an escape of fluid into a body cavity)

40-49:

  1. Abdominal discomfort
  2. Abdominal pain upper
  3. Abscess (pus)
  4. Back pain
  5. Balance disorder
  6. Blood urine present
  7. Burning sensation
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Decreased appetite
  10. Diarrhoea haemorrhagic (bloody diarrhoea)

50-59:

  1. Arthralgia (joint pain)
  2. Atelectasis (partial or complete collapse of the lung)
  3. Blood pressure increased
  4. Bone pain
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Dyskinesia (abnormality or impairment of voluntary movement)
  8. Dyspepsia (indigestion)
  9. Fracture
  10. Joint stiffness

60+:

  1. Abdominal pain
  2. Abdominal pain upper
  3. Blood glucose fluctuation
  4. Chest discomfort
  5. Chest pain
  6. Coronary artery stenosis (narrowing of coronary artery)
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Diarrhoea
  9. Dizziness
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Lexapro and Alli?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alli and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and orlistat (the active ingredients of Lexapro and Alli, respectively), and Lexapro and Alli (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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