Lexapro and Lacosamide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Lacosamide (lacosamide). Common drug interactions include phyllodes tumour among females and seizure among males.
The phase IV clinical study analyzes what interactions people have when they take Lexapro and Lacosamide. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
What is Lacosamide?
Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.
64 people who take Lexapro and Lacosamide together, and have interactions are studied.

What are the common drug interactions of Lexapro and Lacosamide, by gender? *:
female:
- Phyllodes tumour (breast tumour)
- Speech disorder
- Thrombosis (formation of a blood clot inside a blood vessel)
- Dizziness
- Eating disorder
- Gait disturbance
- International normalised ratio increased
- Fall
- Tremor (trembling or shaking movements in one or more parts of your body)
- Dyspnoea (difficult or laboured respiration)
male:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Nausea (feeling of having an urge to vomit)
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Pain
- Confusional state
- Speech disorder
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Diplopia (double vision)
- Pyrexia (fever)
- Cerebral haemorrhage (bleeding within the brain)
What are the common drug interactions of Lexapro and Lacosamide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Overdose
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Weight fluctuation
- Abdominal pain
- Depressed mood
- Emotional distress
- Fear
- Gastroenteritis (inflammation of stomach and intestine)
- Genital haemorrhage (bleeding from genital)
- Injury
30-39:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Alopecia (absence of hair from areas of the body)
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Cardiac arrest
- Dehydration (dryness resulting from the removal of water)
- Drug withdrawal convulsions
- Eye disorder
- Fibroadenoma of breast (breast lump)
- Hypoaesthesia (reduced sense of touch or sensation)
- Intraductal papilloma of breast (tiny wart-like growth in breast tissue)
40-49:
- Overdose
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Memory impairment
- Psychiatric symptom
- Pyrexia (fever)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Agitation (state of anxiety or nervous excitement)
50-59:
- Gait disturbance
- Pain
- Dysuria (painful or difficult urination)
- Ligament sprain (ligament stretched)
- Lipomatosis (multiple soft tissue non cancer tumour in body)
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Cerebral haemorrhage (bleeding within the brain)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dizziness
- Nausea (feeling of having an urge to vomit)
60+:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Fall
- Cystitis (inflammation of the wall of the bladder)
- Drug intolerance (drug sensitivity)
- Essential tremor
- Face injury
- Head injury
- Insomnia (sleeplessness)
- Kidney infection
- Legionella infection (a lung infection caused by bacteria of the species legionella)
What are the existing conditions these people have? *
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 38 people, 59.38%
- Stress And Anxiety: 10 people, 15.62%
- Partial Seizures (seizures which affect only a part of the brain at onset): 9 people, 14.06%
- Pain: 8 people, 12.50%
- Thyroid Diseases: 6 people, 9.38%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 6.25%
- Heart Disease: 4 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Lexapro and Lacosamide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lexapro (91,464 reports)
- Lacosamide (16,601 reports)
Browse all drug interactions of Lexapro and Lacosamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lacosamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lacosamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on escitalopram oxalate and lacosamide (the active ingredients of Lexapro and Lacosamide, respectively), and Lexapro and Lacosamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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