Lexapro and Multihance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Multihance (gadobenate dimeglumine). Common drug interactions include skin disorder among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Multihance. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.



On Jul, 26, 2026

64 people who take Lexapro and Multihance together, and have interactions are studied.

Lexapro and Multihance drug interactions.

What are the common drug interactions of Lexapro and Multihance, by gender? *:

female:

  1. Skin disorder (skin disease)
  2. General physical health deterioration (weak health status)
  3. Scar
  4. Skin lesion
  5. Gait disturbance
  6. Joint stiffness
  7. Pain in extremity
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Asthenia (weakness)
  10. Bone pain

male:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Mobility decreased (ability to move is reduced)
  3. Joint range of motion decreased (disease of joint movement)
  4. Skin hypertrophy (skin cells enlarges)
  5. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  6. Injury
  7. General physical health deterioration (weak health status)
  8. Pain in extremity
  9. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  10. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)

What are the common drug interactions of Lexapro and Multihance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anaphylactic reaction (serious allergic reaction)

20-29:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  4. Fall
  5. Joint lock
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  8. Pain
  9. Peroneal nerve palsy
  10. Vascular calcification (deposits of calcium in the blood vessels)

30-39:

  1. Mobility decreased (ability to move is reduced)
  2. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  3. Pain
  4. Skin hypertrophy (skin cells enlarges)
  5. Skin induration (an abnormally hard spot or area on the skin)
  6. Arthralgia (joint pain)
  7. Skin tightness
  8. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  9. Joint range of motion decreased (disease of joint movement)
  10. Pruritus (severe itching of the skin)

40-49:

  1. Excoriation (to tear or wear off the skin of)
  2. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  3. Injury
  4. Insomnia (sleeplessness)
  5. Joint range of motion decreased (disease of joint movement)
  6. Joint stiffness
  7. Lichenification (thickening and hardening of the skin)
  8. Limb discomfort (discomfort in leg)
  9. Lung disorder (lung disease)
  10. Mobility decreased (ability to move is reduced)

50-59:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pain
  3. Mobility decreased (ability to move is reduced)
  4. Oedema peripheral (superficial swelling)
  5. Scar
  6. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  7. General physical health deterioration (weak health status)
  8. Skin tightness
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Skin induration (an abnormally hard spot or area on the skin)

60+:

  1. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  4. Skin discolouration (change of skin colour)
  5. Skin induration (an abnormally hard spot or area on the skin)
  6. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  7. Back pain
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Joint swelling
  10. Neck pain

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Brain: 23 people, 35.94%
  2. Diabetes: 10 people, 15.62%
  3. Nuclear Magnetic Resonance Imaging Abdominal: 7 people, 10.94%
  4. Pain: 5 people, 7.81%
  5. Sleep Apnea Syndrome: 4 people, 6.25%
  6. Headache (pain in head): 4 people, 6.25%
  7. Brain Stem Syndrome: 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multihance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and gadobenate dimeglumine (the active ingredients of Lexapro and Multihance, respectively), and Lexapro and Multihance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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