Lupron and Xalatan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lupron (leuprolide acetate) and Xalatan (latanoprost). Common drug interactions include acne among females and prostatic specific antigen increased among males.
The phase IV clinical study analyzes what interactions people have when they take Lupron and Xalatan. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.
What is Lupron?
Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.
What is Xalatan?
Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.
55 people who take Lupron and Xalatan together, and have interactions are studied.

What are the common drug interactions of Lupron and Xalatan, by gender? *:
female:
- Acne (skin problems that cause pimples)
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Foot fracture
- Weight increased
male:
- Prostatic specific antigen increased
- Fatigue (feeling of tiredness)
- Decreased appetite
- Malignant neoplasm progression (cancer tumour came back)
- Coma (state of unconsciousness lasting more than six hours)
- Confusional state
- Constipation
- Deafness
- Difficulty in walking
- Dizziness
What are the common drug interactions of Lupron and Xalatan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Acne (skin problems that cause pimples)
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Foot fracture
- Weight increased
50-59:
n/a
60+:
- Pyrexia (fever)
- Nausea (feeling of having an urge to vomit)
- Hyperglycaemia (high blood sugar)
- Muscle weakness (a lack of muscle strength)
- Intraocular pressure increased
- Mass
- Agitation (state of anxiety or nervous excitement)
- Asthenia (weakness)
- Blood magnesium decreased
- Confusional state
What are the existing conditions these people have? *
- Prostate Cancer: 34 people, 61.82%
- Prostate Cancer Metastatic: 4 people, 7.27%
- Muscle Spasms (muscle contraction): 3 people, 5.45%
- High Blood Pressure: 3 people, 5.45%
- High Blood Cholesterol: 3 people, 5.45%
* Approximation only. Some reports may have incomplete information.
Do you take Lupron and Xalatan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lupron and Xalatan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lupron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xalatan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lupron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xalatan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on leuprolide acetate and latanoprost (the active ingredients of Lupron and Xalatan, respectively), and Lupron and Xalatan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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