Lexapro and Sublocade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Sublocade (buprenorphine). Common drug interactions include oedema peripheral among females and drug dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Sublocade. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Sublocade?

Sublocade has active ingredients of buprenorphine. eHealthMe is studying from 4,530 Sublocade users. Check the latest studies of Sublocade.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

18 people who take Lexapro and Sublocade together, and have interactions are studied.

Lexapro and Sublocade drug interactions.

What are the common drug interactions of Lexapro and Sublocade, by gender? *:

female:

Oedema peripheral (superficial swelling)
Chills (felling of cold)
Decreased appetite
Dysphoria (generalized dissatisfaction with life)
Headache (pain in head)
Injection site necrosis (death of body tissue at injection site)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

male:

Drug dependence
Drug abuse
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysuria (painful or difficult urination)
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Lexapro and Sublocade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Oedema peripheral (superficial swelling)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysphoria (generalized dissatisfaction with life)
Dysuria (painful or difficult urination)
Headache (pain in head)
Injection site necrosis (death of body tissue at injection site)
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Injection site pain
Drug abuse

40-49:

Chills (felling of cold)
Decreased appetite
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Insomnia (sleeplessness)
Night sweats (sweating in night)

50-59:

n/a

60+:

Hypersomnia (excessive daytime sleepiness (eds))
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Sleep terror (felling of terror in sleep)

What are the existing conditions these people have? *

Drug Dependence: 13 people, 72.22%
Sleep Disorder: 2 people, 11.11%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 2 people, 11.11%
Local Anaesthesia: 2 people, 11.11%
Insomnia (sleeplessness): 2 people, 11.11%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 11.11%
Stress And Anxiety: 1 person, 5.56%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 5.56%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 5.56%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Lexapro and Sublocade?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously