Lexiscan and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexiscan (regadenoson) and Metformin (metformin hydrochloride). Common drug interactions include myocardial infarction among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Lexiscan and Metformin. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Lexiscan?

Lexiscan has active ingredients of regadenoson. eHealthMe is studying from 4,442 Lexiscan users. Check the latest studies of Lexiscan.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

On Jul, 11, 2026

76 people who take Lexiscan and Metformin together, and have interactions are studied.

Lexiscan and Metformin drug interactions.

What are the common drug interactions of Lexiscan and Metformin, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Altered state of consciousness (altered state of mind)
Atrioventricular block (heart block)
Atrioventricular block first degree (heart block first degree)
Drug hypersensitivity
Electrocardiogram st segment elevation
Heart rate increased
Hypotension (abnormally low blood pressure)
Pain in extremity
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

male:

Dyspnoea (difficult or laboured respiration)
Dizziness
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Scrotal cyst (cyst of scrotum)
Scrotal pain
Scrotal swelling
Sinus arrest (sinus pause)
Testicular pain (pain in testes)
Unresponsive to stimuli

What are the common drug interactions of Lexiscan and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Cardiac failure congestive
Chronic kidney disease
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetic nephropathy (diabetic kidney disease)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hypertensive heart disease
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

40-49:

Dyspnoea (difficult or laboured respiration)
Anaphylactic reaction (serious allergic reaction)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood pressure decreased
Nausea (feeling of having an urge to vomit)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Cellulitis (infection under the skin)
Gas gangrene (bacterial infection that produces gas within tissues)

50-59:

Cellulitis (infection under the skin)
Chest discomfort
Death
Dizziness
Dyspnoea (difficult or laboured respiration)
Gas gangrene (bacterial infection that produces gas within tissues)
Groin abscess (pus in groin)
Groin pain
Hypertension (high blood pressure)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)

60+:

Dyspnoea (difficult or laboured respiration)
Unresponsive to stimuli
Lethargy (tiredness)
Blood pressure increased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Asthenia (weakness)
Loss of consciousness
Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Presyncope

What are the existing conditions these people have? *

Pain: 11 people, 14.47%
Chest Pain: 9 people, 11.84%
High Blood Pressure: 7 people, 9.21%
Type 2 Diabetes: 5 people, 6.58%
High Blood Cholesterol: 5 people, 6.58%
Stress And Anxiety: 4 people, 5.26%
Hypersensitivity: 4 people, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.26%
Cardiac Disorder: 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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