Lialda and Diflucan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lialda (mesalamine) and Diflucan (fluconazole). Common drug interactions include anaemia among females and leukocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Lialda and Diflucan. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

On Jul, 16, 2026

12 people who take Lialda and Diflucan together, and have interactions are studied.

What are the common drug interactions of Lialda and Diflucan, by gender? *:

female:

Anaemia (lack of blood)
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Alanine aminotransferase increased
Alopecia (absence of hair from areas of the body)
Aspartate aminotransferase increased
Blood albumin decreased
Blood alkaline phosphatase increased
Blood glucose increased
Blood thyroid stimulating hormone increased

male:

Leukocytosis (increased white blood cells)
Abdominal pain
Decreased appetite
Diarrhoea
Drug intolerance (drug sensitivity)
Flatulence (flatus expelled through the anus)
Gout (uric acid crystals building up in the body)
Infarction (obstruction of the blood supply to an organ or region of tissue)
Nervousness
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the common drug interactions of Lialda and Diflucan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Anaemia (lack of blood)
Diarrhoea
Drug ineffective
Haematochezia (passage of stools containing blood)
Intestinal ulcer
Red blood cell sedimentation rate increased

60+:

C-reactive protein increased
Diarrhoea
Blood thyroid stimulating hormone increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Colon dysplasia (abnormal growth or development of cells of colon)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glomerular filtration rate increased
Haemoglobin decreased
Liver abscess (pus in liver)
Platelet count increased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 41.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 33.33%
Nausea (feeling of having an urge to vomit): 2 people, 16.67%
Migraine (headache): 2 people, 16.67%
Indigestion: 2 people, 16.67%
Cystic Fibrosis (disease of the secretary glands): 2 people, 16.67%
Abdominal Rigidity: 2 people, 16.67%
Abdominal Pain Lower: 2 people, 16.67%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 8.33%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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