Lidex and Fosamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lidex (fluocinonide) and Fosamax (alendronate sodium). Common drug interactions include herpes simplex among females and diabetic ketoacidosis among males.

The phase IV clinical study analyzes what interactions people have when they take Lidex and Fosamax. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Lidex?

Lidex has active ingredients of fluocinonide. eHealthMe is studying from 1,039 Lidex users. Check the latest studies of Lidex.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,449 Fosamax users. Check the latest studies of Fosamax.

On Nov, 11, 2025

34 people who take Lidex and Fosamax together, and have interactions are studied.

What are the common drug interactions of Lidex and Fosamax, by gender? *:

female:

Herpes simplex (herpes simplex is a common viral infection)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypoxia (low oxygen in tissues)
Impaired healing
Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash)
Lumbar vertebral fracture
Mouth ulceration (mouth ulcers)
Mucosal inflammation (infection of mucous membrane)
Oedema peripheral (superficial swelling)
Oral disorder (mouth disease)

male:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Pancreatitis (inflammation of pancreas)
Asthma
Blood potassium decreased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fibromyalgia (a long-term condition which causes pain all over the body)
Haemoglobin decreased
Herpes simplex ophthalmic (eye infection is caused by a type of herpes simplex virus)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Intervertebral disc protrusion (spinal disc protrusion)

What are the common drug interactions of Lidex and Fosamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Candidiasis (candidiasis or thrush is a fungal infection)
Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Duodenal ulcer
Eye infection
Fracture
Fungal infection
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Pancreatitis (inflammation of pancreas)
Diastolic dysfunction
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Hypertensive emergency
Pain
Abnormal loss of weight
Actinic keratosis (skin disease due to sun exposure)
Acute pulmonary oedema (sudden deposit of fluid in the lung))

What are the existing conditions these people have? *

Hepatitis C: 7 people, 20.59%
Stress And Anxiety: 4 people, 11.76%
Nausea (feeling of having an urge to vomit): 4 people, 11.76%
Nausea And Vomiting: 4 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.76%
Pain: 3 people, 8.82%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.82%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.88%
Hypokalemia (low potassium): 2 people, 5.88%
High Blood Pressure: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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