Linaclotide and Valium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Linaclotide (linaclotide) and Valium (diazepam). Common drug interactions include drug ineffective among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Linaclotide and Valium. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Linaclotide?
Linaclotide has active ingredients of linaclotide. eHealthMe is studying from 2,197 Linaclotide users. Check the latest studies of Linaclotide.
What is Valium?
Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.
12 people who take Linaclotide and Valium together, and have interactions are studied.

What are the common drug interactions of Linaclotide and Valium, by gender? *:
female:
- Drug ineffective
- Cardiac failure congestive
- Chest pain
- Deafness
- Dependence
- Diarrhoea
- Fungal infection
- Liver disorder (liver diseases)
- Migraine (headache)
- Pleural fibrosis (formation of fibrous tissue in lung)
male:
- Arthralgia (joint pain)
- Fatigue (feeling of tiredness)
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Faecaloma (hard mass of fecal matter)
- Flatulence (flatus expelled through the anus)
- Gastroenteritis (inflammation of stomach and intestine)
- Hyperhidrosis (abnormally increased sweating)
- Libido decreased (loss of interest in sex)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
What are the common drug interactions of Linaclotide and Valium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Faecaloma (hard mass of fecal matter)
- Gastroenteritis (inflammation of stomach and intestine)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Pyrexia (fever)
- Vomiting
- Cardiac failure congestive
- Chest pain
- Deafness
50-59:
- Myalgia (muscle pain)
- Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
- Nightmare (unpleasant dream)
- Overdose
- Pulmonary embolism (blockage of the main artery of the lung)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
60+:
- Drug ineffective
- Anal fissure
- Hypertension (high blood pressure)
- Insomnia (sleeplessness)
- Nocturia (the need to get up in the night to urinate)
- Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
- Procedural pain
- Prostate cancer
- Pruritus (severe itching of the skin)
- Restless legs syndrome (a powerful urge to move your legs)
What are the existing conditions these people have? *
- Constipation: 4 people, 33.33%
- Irritable Bowel Syndrome: 3 people, 25.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 16.67%
- Pain: 2 people, 16.67%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 16.67%
- Headache (pain in head): 1 person, 8.33%
- Depression: 1 person, 8.33%
- Drowsiness: 1 person, 8.33%
- Fungal Infection: 1 person, 8.33%
- Gastrointestinal Pain: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Linaclotide and Valium?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Linaclotide (2,197 reports)
- Valium (48,647 reports)
Browse all drug interactions of Linaclotide and Valium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Linaclotide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Linaclotide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on linaclotide and diazepam (the active ingredients of Linaclotide and Valium, respectively), and Linaclotide and Valium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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