Loniten and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loniten (minoxidil) and Protonix (pantoprazole sodium). Common drug interactions include activities of daily living impaired among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Loniten and Protonix. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Loniten?

Loniten has active ingredients of minoxidil. eHealthMe is studying from 363 Loniten users. Check the latest studies of Loniten.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

On Jul, 10, 2026

30 people who take Loniten and Protonix together, and have interactions are studied.

What are the common drug interactions of Loniten and Protonix, by gender? *:

female:

Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chest pain
Dry skin
Emotional distress
Joint contracture (a permanent shortening of a muscle or joint)
Joint stiffness
Mobility decreased (ability to move is reduced)
Muscular weakness (muscle weakness)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Weight bearing difficulty (difficulty due to weight of thigh fat deposition)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Diarrhoea
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Gout (uric acid crystals building up in the body)

What are the common drug interactions of Loniten and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pneumonia
Gastroenteritis (inflammation of stomach and intestine)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

30-39:

Anaemia (lack of blood)
Hip arthroplasty
Hyperkalaemia (damage to or disease of the kidney)
Hypoxia (low oxygen in tissues)
Leukopenia (less number of white blood cells in blood)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Weight bearing difficulty (difficulty due to weight of thigh fat deposition)
Abdominal pain
Blood pressure decreased
Breath sounds

40-49:

Drug hypersensitivity
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Anaemia (lack of blood)
Appetite disorder (abnormal eating habits)
Arthralgia (joint pain)
Asthenia (weakness)
Chills (felling of cold)
Chronic kidney disease
Diarrhoea
Dizziness

50-59:

Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dry skin
Emotional distress
Joint contracture (a permanent shortening of a muscle or joint)
Joint stiffness
Mobility decreased (ability to move is reduced)
Muscular weakness (muscle weakness)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

60+:

Chronic kidney disease
Renal injury (kidney injury)
Anaphylactic reaction (serious allergic reaction)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Overdose

What are the existing conditions these people have? *

Pain: 12 people, 40.00%
High Blood Pressure: 11 people, 36.67%
Diabetes: 9 people, 30.00%
Anaemia (lack of blood): 8 people, 26.67%
Nuclear Magnetic Resonance Imaging Brain: 6 people, 20.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 20.00%
Nausea And Vomiting: 4 people, 13.33%
Nausea (feeling of having an urge to vomit): 4 people, 13.33%
High Blood Cholesterol: 4 people, 13.33%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 4 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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