Lopid and Aranesp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopid (gemfibrozil) and Aranesp (darbepoetin alfa). Common drug interactions include renal failure acute among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Lopid and Aranesp. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

What is Aranesp?

Aranesp has active ingredients of darbepoetin alfa. It is often used in anemia. eHealthMe is studying from 54,331 Aranesp users. Check the latest studies of Aranesp.



On Jul, 07, 2026

38 people who take Lopid and Aranesp together, and have interactions are studied.

Lopid and Aranesp drug interactions.

What are the common drug interactions of Lopid and Aranesp, by gender? *:

female:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Ankle fracture
  3. Blindness transient (sudden loss of vision)
  4. Blood creatinine increased
  5. Blood urea increased
  6. Bone density decreased
  7. Chronic kidney disease
  8. Death
  9. Dizziness
  10. Emotional distress

male:

  1. Renal failure (kidney dysfunction)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  4. Diarrhoea
  5. Epistaxis (bleed from the nose)
  6. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  7. General physical health deterioration (weak health status)
  8. Hypotension (abnormally low blood pressure)
  9. Joint contracture (a permanent shortening of a muscle or joint)
  10. Joint range of motion decreased (disease of joint movement)

What are the common drug interactions of Lopid and Aranesp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Hyperthermia (body temperature greatly above normal)
  2. Pyrexia (fever)

40-49:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Depression
  3. Erythema (redness of the skin)
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  5. Oedema peripheral (superficial swelling)
  6. Abdominal pain
  7. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  8. Anxiety
  9. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  10. Arthralgia (joint pain)

50-59:

  1. Quadriparesis (muscle weakness affecting all four limbs)
  2. Rash pruritic (redness with itching)
  3. Skin hypertrophy (skin cells enlarges)
  4. Skin lesion
  5. Skin tightness
  6. Tooth loss
  7. Vomiting
  8. White blood cell count decreased
  9. Bacteriuria (presence of bacteria in urine)
  10. Chest pain

60+:

  1. Blood creatinine increased
  2. Renal failure (kidney dysfunction)
  3. Red blood cell count decreased
  4. Renal failure acute (rapid kidney dysfunction)
  5. Abdominal discomfort
  6. Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
  7. Anaemia (lack of blood)
  8. Aortic arteriosclerosis (hardening of the aortic arteries)
  9. Aseptic necrosis bone
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Chronic Renal Failure (kidney failure): 6 people, 15.79%
  2. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 5 people, 13.16%
  3. Nuclear Magnetic Resonance Imaging Brain: 3 people, 7.89%
  4. Metastases To Bone (cancer spreads to bone): 2 people, 5.26%
  5. Hiv Infection: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Lopid and Aranesp?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lopid and Aranesp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lopid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aranesp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lopid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aranesp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gemfibrozil and darbepoetin alfa (the active ingredients of Lopid and Aranesp, respectively), and Lopid and Aranesp (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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