Loprox and Paxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loprox (ciclopirox) and Paxil (paroxetine hydrochloride). Common drug interactions include nodule among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Loprox and Paxil. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Loprox?

Loprox has active ingredients of ciclopirox. eHealthMe is studying from 618 Loprox users. Check the latest studies of Loprox.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

On Jul, 17, 2026

12 people who take Loprox and Paxil together, and have interactions are studied.

What are the common drug interactions of Loprox and Paxil, by gender? *:

female:

Nodule (a growth of abnormal tissue)
Pancreatitis (inflammation of pancreas)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
Vaginal infection
Vertigo
Fall
Femur fracture
Foot fracture
Fracture nonunion (permanent failure of healing following a broken bone)

male:

Hypotension (abnormally low blood pressure)
Pain
Chest pain
Chronic obstructive airways disease
Colonic polyp (extra part of colon tissue grow in intestine)
Cor pulmonale (enlargement of the right ventricle of the heart)
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Loprox and Paxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pancreatitis (inflammation of pancreas)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Sleep disorder
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
Syncope (loss of consciousness with an inability to maintain postural tone)
Vaginal infection
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Vertigo
Hypertension (high blood pressure)
Anaemia (lack of blood)

50-59:

Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Anaemia (lack of blood)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Back pain
Chest pain
Chronic obstructive airways disease
Colonic polyp (extra part of colon tissue grow in intestine)
Cor pulmonale (enlargement of the right ventricle of the heart)
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
Dehydration (dryness resulting from the removal of water)

60+:

Fall
Femur fracture
Fracture displacement
Metastatic neoplasm (spreadable cancer tumour)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Synovial cyst (cyst of joint filled with synovial fluid)
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
Pathological fracture (broken bone caused by disease)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 33.33%
High Blood Pressure: 2 people, 16.67%
Bipolar Disorder (mood disorder): 2 people, 16.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 16.67%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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