Lopurin and Acular drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopurin (allopurinol) and Acular (ketorolac tromethamine). Common drug interactions include urinary tract infection among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lopurin and Acular. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Lopurin?

Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,797 Lopurin users. Check the latest studies of Lopurin.

What is Acular?

Acular has active ingredients of ketorolac tromethamine. eHealthMe is studying from 1,125 Acular users. Check the latest studies of Acular.

On Jul, 05, 2026

58 people who take Lopurin and Acular together, and have interactions are studied.

What are the common drug interactions of Lopurin and Acular, by gender? *:

female:

Urinary tract infection
Dry eye (lack of adequate tears)
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Migraine with aura (headache with vision weakness)
Type 2 diabetes mellitus
Chronic kidney disease
Haemorrhage (bleeding)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Gastrointestinal ulcer
Infection

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Death
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Infection
Iridocele
Iris disorder
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
Photosensitive rash
Rash pruritic (redness with itching)

What are the common drug interactions of Lopurin and Acular, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Nephrolithiasis (calculi in the kidneys)
Hospitalisation
Hypokalaemia (low potassium)
Urinary tract infection
Infection
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Back pain
Blood chloride increased
Blood creatinine increased

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Rash
Blood glucose increased
Cardiac arrest
Death
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Eye infection
Eye pain
Henoch-schonlein purpura (inflammation of the blood vessels in the skin and other body organs)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 31 people, 53.45%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 31 people, 53.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 18.97%
Pain: 6 people, 10.34%
High Blood Pressure: 6 people, 10.34%
Headache (pain in head): 4 people, 6.90%
Asthma: 4 people, 6.90%
High Blood Cholesterol: 3 people, 5.17%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 5.17%
Cardiac Disorder: 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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