Loraz and Estraderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Estraderm (estradiol). Common drug interactions include pain in extremity among females.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Estraderm. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Estraderm?

Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.

On Jul, 20, 2026

42 people who take Loraz and Estraderm together, and have interactions are studied.

What are the common drug interactions of Loraz and Estraderm, by gender? *:

female:

Pain in extremity
Hypertension (high blood pressure)
Headache (pain in head)
Breast cancer female
Adnexa uteri mass (ovarian cysts)
Adrenal mass
Carbohydrate antigen 125 increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colonic polyp (extra part of colon tissue grow in intestine)
Constipation

male:

n/a

What are the common drug interactions of Loraz and Estraderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Abdominal pain lower
Abdominal pain upper
Abdominal symptom
Acute sinusitis
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bladder disorder
Blood alkaline phosphatase increased
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast cancer

40-49:

Abdominal discomfort
Abnormal faeces (abnormal stool)
Back pain
Fracture
Headache (pain in head)
Incisional hernia, obstructive (incisional hernia without mention of obstruction or gangrene)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Tinnitus (a ringing in the ears)

50-59:

Dyspnoea (difficult or laboured respiration)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Renal failure (kidney dysfunction)
Spider naevus (small dilated blood vessels near the surface of the skin)
Syncope (loss of consciousness with an inability to maintain postural tone)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Fatigue (feeling of tiredness)

60+:

Pain in extremity
Dizziness
Erythema (redness of the skin)
Gout (uric acid crystals building up in the body)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Joint swelling
Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
Scar
Suicidal ideation

What are the existing conditions these people have? *

Menopausal Symptoms: 8 people, 19.05%
Menopause (end of monthly cycles in women): 7 people, 16.67%
High Blood Pressure: 7 people, 16.67%
High Blood Cholesterol: 6 people, 14.29%
Insomnia (sleeplessness): 6 people, 14.29%
Fungal Infection: 4 people, 9.52%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 9.52%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 9.52%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 9.52%
Depression: 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Loraz and Estraderm?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously