Losartan potassium and Macitentan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Losartan potassium (losartan potassium) and Macitentan (macitentan). Common drug interactions include dyspnoea among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Losartan potassium and Macitentan. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Losartan potassium?

Losartan potassium has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 51,511 Losartan potassium users. Check the latest studies of Losartan potassium.

What is Macitentan?

Macitentan has active ingredients of macitentan. eHealthMe is studying from 7,371 Macitentan users. Check the latest studies of Macitentan.

On Jul, 19, 2026

26 people who take Losartan potassium and Macitentan together, and have interactions are studied.

Losartan potassium and Macitentan drug interactions.

What are the common drug interactions of Losartan Potassium and Macitentan, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Anaemia (lack of blood)
Fatigue (feeling of tiredness)
Productive cough
Oedema peripheral (superficial swelling)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Pyrexia (fever)

male:

Death
Diarrhoea
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Mitral valve disease (disease of mitral valve of heart)
Respiratory tract congestion (blockage on respiratory system)
Dyspnoea (difficult or laboured respiration)
Productive cough
Renal impairment (severely reduced kidney function)
Left ventricular failure (left ventricle fails to contract forcefully)
Arrhythmia (irregular heartbeat)

What are the common drug interactions of Losartan Potassium and Macitentan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaemia (lack of blood)
Haemoglobin decreased
Platelet count decreased
White blood cell count decreased

50-59:

Oedema peripheral (superficial swelling)
Infected skin ulcer
Cardiac failure
Cardiac failure congestive
Dyspnoea exertional (breathlessness or shortness of breath)
Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
Ejection fraction decreased (systolic heart failure)
Electrocardiogram qt prolonged
Left ventricular dysfunction
Orthopnoea (shortness of breath (dyspnea) when lying down)

60+:

Dyspnoea (difficult or laboured respiration)
Productive cough
Mitral valve disease (disease of mitral valve of heart)
Pneumonia
Respiratory tract congestion (blockage on respiratory system)
Left ventricular failure (left ventricle fails to contract forcefully)
Ankle fracture
Arrhythmia (irregular heartbeat)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Cardiac valve disease (heart valve disease)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 15 people, 57.69%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 8 people, 30.77%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 11.54%
High Blood Cholesterol: 3 people, 11.54%
Cardiac Disorder: 3 people, 11.54%
Rickets (softening of bones): 2 people, 7.69%
Magnesium Deficiency (lack of magnesium): 2 people, 7.69%
Iron Deficiency Anaemia: 2 people, 7.69%
Hypokalemia (low potassium): 2 people, 7.69%
Hypersensitivity: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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