Lotrisone and Hydramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lotrisone (betamethasone dipropionate; clotrimazole) and Hydramine (diphenhydramine hydrochloride). Common drug interactions include asthenia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Lotrisone and Hydramine. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Lotrisone?

Lotrisone has active ingredients of betamethasone dipropionate; clotrimazole. eHealthMe is studying from 1,819 Lotrisone users. Check the latest studies of Lotrisone.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

On Jul, 20, 2026

47 people who take Lotrisone and Hydramine together, and have interactions are studied.

Lotrisone and Hydramine drug interactions.

What are the common drug interactions of Lotrisone and Hydramine, by gender? *:

female:

Asthenia (weakness)
Back pain
Coma (state of unconsciousness lasting more than six hours)
Constipation
Haemoglobin decreased
Hypokalaemia (low potassium)
Hypotension (abnormally low blood pressure)
Impaired gastric emptying
Joint stiffness
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

male:

Pain
Fatigue (feeling of tiredness)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Automatic bladder (nerve impulses between the bladder and the spinal cord remain intact and the bladder can be trained to empty by reflex (spastic) action)
Bladder pain
Crying
Dependence
Disturbance in attention
Dizziness

What are the common drug interactions of Lotrisone and Hydramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Allergen nos skin test positive
Antinuclear factor positive
Arthralgia (joint pain)
Blood immunoglobulin e increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cardiomegaly (increased size of heart than normal)
Chest pain
Concussion (short loss of normal brain function in response to a head injury)

20-29:

n/a

30-39:

Abdominal hernia
Abdominal pain
Back pain
Blood pressure increased
Cardiac failure congestive
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)

40-49:

Actinomycosis (infection that causes sores, or abscesses)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Back pain
Balance disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone pain
Breast cancer metastatic
Breast mass
Cardiomegaly (increased size of heart than normal)

50-59:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Cellulitis (infection under the skin)
Death
Rash

60+:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Hypokalaemia (low potassium)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Rales (an abnormal respiratory sound characterized by fine crackles)
Acute respiratory failure
Blood magnesium increased
Blood phosphorus increased
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 14.89%
Depression: 5 people, 10.64%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 8.51%
Sleep Disorder: 3 people, 6.38%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 6.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.38%
Jock Itch (fungal infection of the groin and upper thighs): 3 people, 6.38%
Irritability: 3 people, 6.38%
Hypersensitivity: 3 people, 6.38%
Hiv Infection: 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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