Lozol and Zetia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lozol (indapamide) and Zetia (ezetimibe). Common drug interactions include oral pain among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Lozol and Zetia. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Lozol?

Lozol has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 1,652 Lozol users. Check the latest studies of Lozol.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.



On Jul, 15, 2026

48 people who take Lozol and Zetia together, and have interactions are studied.

Lozol and Zetia drug interactions.

What are the common drug interactions of Lozol and Zetia, by gender? *:

female:

  1. Oral pain
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Pelvic pain
  4. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  5. Rectal haemorrhage (bleeding from anus)
  6. Spinal compression fracture (fracture due to spinal compression on bone)
  7. Swelling face
  8. Tongue oedema (swelling of tongue)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Depression

male:

  1. Cardiac disorder
  2. Cardiogenic shock (inadequate circulation of blood)
  3. Blood glucose increased
  4. Carotid artery stenosis (narrowing of carotid artery)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Constipation
  8. Cough
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Disease recurrence

What are the common drug interactions of Lozol and Zetia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Urinary tract infection
  2. Vision blurred
  3. Visual impairment
  4. Blood glucose increased
  5. Headache (pain in head)
  6. Blood glucose decreased
  7. Dizziness
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Pruritus (severe itching of the skin)
  10. Abdominal discomfort

60+:

  1. Chronic kidney disease
  2. Alanine aminotransferase increased
  3. Cardiogenic shock (inadequate circulation of blood)
  4. Depression
  5. Flatulence (flatus expelled through the anus)
  6. Haemorrhage intracranial (bleeding within the skull)
  7. Headache (pain in head)
  8. Hypovolaemic shock (shock caused by severe blood or fluid loss)
  9. Nausea (feeling of having an urge to vomit)
  10. Cough

What are the existing conditions these people have? *

  1. Pain: 12 people, 25.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.42%
  3. Cardiac Disorder: 5 people, 10.42%
  4. Multiple Allergies (allergy to multiple agents): 4 people, 8.33%
  5. Erection Problems: 4 people, 8.33%
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 8.33%
  7. Infection: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lozol and Zetia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lozol and Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lozol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lozol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zetia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on indapamide and ezetimibe (the active ingredients of Lozol and Zetia, respectively), and Lozol and Zetia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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