Lupron and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lupron (leuprolide acetate) and Hydroxyurea (hydroxyurea). Common drug interactions include abdominal discomfort among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Lupron and Hydroxyurea. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

On Jul, 13, 2026

20 people who take Lupron and Hydroxyurea together, and have interactions are studied.

Lupron and Hydroxyurea drug interactions.

What are the common drug interactions of Lupron and Hydroxyurea, by gender? *:

female:

Abdominal discomfort
Abdominal pain
Abdominal pain upper
Anger
Anxiety
Asthenia (weakness)
Blood pressure diastolic increased
Blood pressure increased
Blood pressure systolic increased
Chest pain

male:

Abdominal pain upper
Decreased appetite
Dyspnoea exertional (breathlessness or shortness of breath)
Weight decreased
Acute respiratory failure
Affect lability (emotional incontinence)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Deafness
Erectile dysfunction
Haematuria (presence of blood in urine)

What are the common drug interactions of Lupron and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Nausea (feeling of having an urge to vomit)
Vomiting
Acute chest syndrome (acute chest pain, fever and difficulty breathing)
Decreased appetite

40-49:

Abdominal discomfort
Abdominal pain
Abdominal pain upper
Anger
Anxiety
Asthenia (weakness)
Blood pressure diastolic increased
Blood pressure increased
Blood pressure systolic increased
Chest pain

50-59:

n/a

60+:

Death
Hallucination (an experience involving the perception of something not present)
Haematuria (presence of blood in urine)
Pneumonia
Prostatic specific antigen increased
Renal impairment (severely reduced kidney function)
Weight decreased
Acute respiratory failure
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

Prostate Cancer: 7 people, 35.00%
Parkinson's Disease: 3 people, 15.00%
Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 10.00%
Urinary Tract Infection: 1 person, 5.00%
Prostatic Specific Antigen Decreased: 1 person, 5.00%
Menopause (end of monthly cycles in women): 1 person, 5.00%
Hypokalemia (low potassium): 1 person, 5.00%
High Blood Pressure: 1 person, 5.00%
Carcinoid Tumor: 1 person, 5.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lupron and Hydroxyurea?

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