1. Home
  2. Analysis
  3. Lupron
  4. Imodium-a-d

Lupron and Imodium a-d drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lupron (leuprolide acetate) and Imodium a-d (loperamide hydrochloride). Common drug interactions include nausea among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Lupron and Imodium a-d. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

What is Imodium a-d?

Imodium a-d has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 8,944 Imodium a-d users. Check the latest studies of Imodium a-d.

On Jul, 10, 2026

25 people who take Lupron and Imodium a-d together, and have interactions are studied.

Lupron and Imodium a-d drug interactions.

What are the common drug interactions of Lupron and Imodium A-D, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Abdominal pain upper
  3. Headache (pain in head)
  4. Vomiting

male:

  1. Fatigue (feeling of tiredness)
  2. Anaemia (lack of blood)
  3. Myalgia (muscle pain)
  4. Prostatic specific antigen increased
  5. Tooth extraction
  6. Vomiting
  7. Abdominal pain upper
  8. Anxiety
  9. Asthenia (weakness)
  10. Blood pressure increased

What are the common drug interactions of Lupron and Imodium A-D, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chills (felling of cold)
  2. Fatigue (feeling of tiredness)
  3. Nausea (feeling of having an urge to vomit)
  4. White blood cell count decreased

50-59:

  1. Abdominal pain upper
  2. Anaemia (lack of blood)
  3. Cerebral haemorrhage (bleeding within the brain)
  4. Confusional state
  5. Headache (pain in head)
  6. Nausea (feeling of having an urge to vomit)
  7. Overdose
  8. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  9. Thrombocytopenia (decrease of platelets in blood)
  10. Thrombosis (formation of a blood clot inside a blood vessel)

60+:

  1. Fatigue (feeling of tiredness)
  2. Anaemia (lack of blood)
  3. Prostatic specific antigen increased
  4. Asthenia (weakness)
  5. Blood pressure increased
  6. Blood testosterone decreased
  7. Burning sensation
  8. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  9. Decreased appetite
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

  1. Prostate Cancer: 13 people, 52.00%
  2. Sleep Disorder: 2 people, 8.00%
  3. Pain: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lupron and Imodium a-d?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lupron and Imodium a-d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imodium a-d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lupron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imodium a-d and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate and loperamide hydrochloride (the active ingredients of Lupron and Imodium a-d, respectively), and Lupron and Imodium a-d (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.