Lysine and Creatine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lysine (lysine) and Creatine (creatine). Common drug interactions include anxiety among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Lysine and Creatine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Lysine?

Lysine has active ingredients of lysine. It is often used in herpes labialis (oral herpes simplex). eHealthMe is studying from 16,525 Lysine users. Check the latest studies of Lysine.

What is Creatine?

Creatine has active ingredients of creatine. It is often used in muscle mass. eHealthMe is studying from 1,391 Creatine users. Check the latest studies of Creatine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

17 people who take Lysine and Creatine together, and have interactions are studied.

What are the common drug interactions of Lysine and Creatine, by gender? *:

female:

Anxiety
Blindness transient (sudden loss of vision)
Decreased appetite
Dizziness
Drug ineffective
Dry mouth
Fatigue (feeling of tiredness)
Hysterectomy
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment

male:

Abdominal distension
Acute myocardial infarction (acute heart attack)
Head discomfort
Headache (pain in head)
Intervertebral disc protrusion (spinal disc protrusion)
Liver disorder (liver diseases)
Drug ineffective
Hot flush (sudden feelings of heat)
Injection site mass
Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the common drug interactions of Lysine and Creatine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Parotitis (inflammation of a parotid gland)

20-29:

Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Oedema (fluid collection in tissue)
Papule
Pruritus (severe itching of the skin)
Respiratory failure (inadequate gas exchange by the respiratory system)
Swelling
Urticaria (rash of round, red welts on the skin that itch intensely)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

30-39:

Drug ineffective

40-49:

n/a

50-59:

Acute myocardial infarction (acute heart attack)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Intervertebral disc protrusion (spinal disc protrusion)
Liver disorder (liver diseases)
Breast cancer metastatic

60+:

Hot flush (sudden feelings of heat)
Injection site mass

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 41.18%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 41.18%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 17.65%
Cystic Fibrosis (disease of the secretary glands): 2 people, 11.76%
Erection Problems: 2 people, 11.76%
Genital Herpes (herpes infection of genital): 2 people, 11.76%
Spider Vein (small dilated blood vessels near the surface of the skin): 2 people, 11.76%
Insomnia (sleeplessness): 1 person, 5.88%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 1 person, 5.88%
Depression: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Lysine and Creatine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously