M.v.i. and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take M.v.i. (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Simvastatin (simvastatin). Common drug interactions include drug ineffective among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take M.v.i. and Simvastatin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is M.v.i.?

M.v.i. has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. eHealthMe is studying from 2,498 M.v.i. users. Check the latest studies of M.v.i..

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.



On Jul, 19, 2026

77 people who take M.v.i. and Simvastatin together, and have interactions are studied.

M.v.i. and Simvastatin drug interactions.

What are the common drug interactions of M.V.I. and Simvastatin, by gender? *:

female:

  1. Drug ineffective
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Haematuria present (presence of blood in urine due to trauma)
  4. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  5. Hot flush (sudden feelings of heat)
  6. Hypoglycaemia (deficiency of glucose in the bloodstream)
  7. Immunosuppressant drug level increased
  8. Joint stiffness
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

male:

  1. Diarrhoea
  2. Drug toxicity
  3. Blood creatine phosphokinase increased
  4. Blood urea increased
  5. Dizziness
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  8. Haematochezia (passage of stools containing blood)
  9. International normalised ratio increased
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of M.V.I. and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Appendicitis (inflammation of the appendix)
  2. Neuroma (tumour of nerve tissue)
  3. Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)

40-49:

  1. Blood creatine phosphokinase increased
  2. Myositis (inflammation of the muscles)

50-59:

  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Blood creatinine increased
  3. Blood urea increased
  4. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
  7. Depression
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Digoxin toxicity
  10. Discomfort

60+:

  1. Drug toxicity
  2. Nausea (feeling of having an urge to vomit)
  3. Haematochezia (passage of stools containing blood)
  4. Hyperhidrosis (abnormally increased sweating)
  5. International normalised ratio increased
  6. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  7. Pulmonary oedema (fluid accumulation in the lungs)
  8. Rash
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Weight decreased

What are the existing conditions these people have? *

  1. Pain: 5 people, 6.49%
  2. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 6.49%
  3. Depression: 5 people, 6.49%
  4. Insomnia (sleeplessness): 4 people, 5.19%
  5. High Blood Pressure: 4 people, 5.19%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of M.v.i. and Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of M.v.i.:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between M.v.i. and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simvastatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and simvastatin (the active ingredients of M.v.i. and Simvastatin, respectively), and M.v.i. and Simvastatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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