Magnesium and Propylthiouracil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Magnesium (magnesium) and Propylthiouracil (propylthiouracil). Common drug interactions include thyroid disorder among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Magnesium and Propylthiouracil. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,147 Magnesium users. Check the latest studies of Magnesium.

What is Propylthiouracil?

Propylthiouracil has active ingredients of propylthiouracil. It is often used in hyperthyroidism. eHealthMe is studying from 2,545 Propylthiouracil users. Check the latest studies of Propylthiouracil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

24 people who take Magnesium and Propylthiouracil together, and have interactions are studied.

Magnesium and Propylthiouracil drug interactions.

What are the common drug interactions of Magnesium and Propylthiouracil, by gender? *:

female:

  1. Thyroid disorder (thyroid diseases)
  2. Weight decreased
  3. Dysmorphism (difference of body structure that is suggestive of a congenital disorder)
  4. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  7. Chronic kidney disease
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Renal failure (kidney dysfunction)
  10. Renal impairment (severely reduced kidney function)

male:

  1. Cardiac failure congestive
  2. Nephropathy (damage to or disease of a kidney)
  3. Blood creatinine increased
  4. Blood glucose increased
  5. Blood pressure systolic increased
  6. Blood urea increased
  7. Blood urine present
  8. Body temperature increased
  9. Cerebral infarction (less blood supply to brain resulting tissue damage)
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Magnesium and Propylthiouracil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hepatic failure (liver failure)
  2. Live birth
  3. Maternal exposure during pregnancy (use of substance during pregnancy)
  4. Normal newborn

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Abdominal pain
  2. Fatigue (feeling of tiredness)
  3. Abdominal pain upper
  4. Alanine aminotransferase increased
  5. Arthralgia (joint pain)
  6. Blood pressure increased
  7. Diarrhoea
  8. Fungal infection
  9. Head discomfort
  10. Headache (pain in head)

60+:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Cerebral infarction (less blood supply to brain resulting tissue damage)
  4. Death
  5. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  6. Gait disturbance
  7. Hyperkalaemia (damage to or disease of the kidney)
  8. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

  1. High Blood Pressure: 7 people, 29.17%
  2. Insomnia (sleeplessness): 6 people, 25.00%
  3. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 5 people, 20.83%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 20.83%
  5. High Blood Cholesterol: 3 people, 12.50%
  6. Thyroid Diseases: 3 people, 12.50%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 12.50%
  8. Skin Disorder (skin disease): 3 people, 12.50%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 12.50%
  10. Blood Pressure Abnormal: 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Magnesium and Propylthiouracil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Magnesium and Propylthiouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Propylthiouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propylthiouracil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on magnesium and propylthiouracil (the active ingredients of Magnesium and Propylthiouracil, respectively), and Magnesium and Propylthiouracil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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