Mannose and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mannose (d - mannose) and Ibuprofen (ibuprofen). Common drug interactions include cataract among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Mannose and Ibuprofen. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Mannose?

Mannose has active ingredients of d - mannose. eHealthMe is studying from 875 Mannose users. Check the latest studies of Mannose.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.



On Jul, 25, 2026

42 people who take Mannose and Ibuprofen together, and have interactions are studied.

Mannose and Ibuprofen drug interactions.

What are the common drug interactions of Mannose and Ibuprofen, by gender? *:

female:

  1. Cataract (clouding of the lens inside the eye)
  2. Muscular weakness (muscle weakness)
  3. Alopecia (absence of hair from areas of the body)
  4. Throat irritation
  5. Uterine enlargement
  6. Fatigue (feeling of tiredness)
  7. Initial insomnia (feeling of inadequate or poor-quality sleep)
  8. Insomnia (sleeplessness)
  9. Blood cholesterol increased
  10. Blood pressure increased

male:

  1. Insomnia (sleeplessness)
  2. Muscle spasms (muscle contraction)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Urinary tract infection

What are the common drug interactions of Mannose and Ibuprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Erythema (redness of the skin)
  2. Overdose
  3. Pyrexia (fever)
  4. Rash macular (small, flat red spots)

20-29:

  1. Constipation
  2. Insomnia (sleeplessness)
  3. Nocturia (the need to get up in the night to urinate)
  4. Postoperative wound infection

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  6. Cerebral disorder (brain disease)
  7. Dry skin
  8. Fatigue (feeling of tiredness)
  9. Flushing (the warm, red condition of human skin)
  10. Gait disturbance

50-59:

  1. Mobility decreased (ability to move is reduced)
  2. Nasopharyngitis (inflammation of the nasopharynx)
  3. Pain in extremity
  4. Platelet count decreased
  5. Rash
  6. Tooth fracture
  7. Urinary tract infection
  8. Urogenital fistula
  9. Wound
  10. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

  1. Hysterectomy
  2. Post procedural haemorrhage (post procedural bleeding)
  3. Burning sensation
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Drug specific antibody present
  6. Escherichia urinary tract infection (urinary tract infection by escherichia coli)
  7. Eye pain
  8. Eye swelling
  9. Hyperglycaemia (high blood sugar)
  10. Intraocular pressure increased

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 12 people, 28.57%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 26.19%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 23.81%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 10 people, 23.81%
  5. Nasopharyngitis (inflammation of the nasopharynx): 8 people, 19.05%
  6. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 8 people, 19.05%
  7. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 7 people, 16.67%
  8. Gait Disturbance: 5 people, 11.90%
  9. Progressive Relapsing Multiple Sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord or both): 4 people, 9.52%
  10. High Blood Pressure: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Mannose and Ibuprofen?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mannose and Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mannose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mannose and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibuprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on d - mannose and ibuprofen (the active ingredients of Mannose and Ibuprofen, respectively), and Mannose and Ibuprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: