Maxolon and Zide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Maxolon (metoclopramide hydrochloride) and Zide (hydrochlorothiazide). Common drug interactions include gastroenteritis among females and atrial fibrillation among males.
The phase IV clinical study analyzes what interactions people have when they take Maxolon and Zide. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Maxolon?
Maxolon has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,977 Maxolon users. Check the latest studies of Maxolon.
What is Zide?
Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.
13 people who take Maxolon and Zide together, and have interactions are studied.

What are the common drug interactions of Maxolon and Zide, by gender? *:
female:
- Gastroenteritis (inflammation of stomach and intestine)
- Haematuria (presence of blood in urine)
- Haemorrhage (bleeding)
- Infection
- Death
- Dehydration (dryness resulting from the removal of water)
- Gastroenteritis salmonella (inflammation of stomach and intestine caused by salmonella bacteria)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Renal failure acute (rapid kidney dysfunction)
- Renal impairment (severely reduced kidney function)
male:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Haemoglobin decreased
- Drug ineffective
- Erectile dysfunction
- Fall
- Femoral neck fracture (neck of femur bone fracture)
- General physical health deterioration (weak health status)
- Heart rate increased
- Hemiparesis (weakness on one side of the body)
- Hydrocephalus (water on the brain)
What are the common drug interactions of Maxolon and Zide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Haematuria (presence of blood in urine)
- Haemorrhage (bleeding)
- Infection
40-49:
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
50-59:
- Gastroenteritis (inflammation of stomach and intestine)
- Death
- Renal failure acute (rapid kidney dysfunction)
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Haemoglobin decreased
- Cerebral ventricle dilatation (enlargement of ventricle of brain)
- Dehydration (dryness resulting from the removal of water)
- Drug ineffective
- Erectile dysfunction
- Fall
- Femoral neck fracture (neck of femur bone fracture)
- Gastroenteritis salmonella (inflammation of stomach and intestine caused by salmonella bacteria)
- General physical health deterioration (weak health status)
What are the existing conditions these people have? *
- Pain: 5 people, 38.46%
- Neuralgia (pain in one or more nerves): 3 people, 23.08%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 23.08%
- Cerebral Haemorrhage (bleeding within the brain): 3 people, 23.08%
- Hiv Infection: 2 people, 15.38%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 15.38%
- Fever: 1 person, 7.69%
- Bladder Transitional Cell Carcinoma (types of bladder cancer): 1 person, 7.69%
- Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 1 person, 7.69%
- Cancer Pain: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Maxolon and Zide?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Maxolon and Zide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Maxolon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxolon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metoclopramide hydrochloride and hydrochlorothiazide (the active ingredients of Maxolon and Zide, respectively), and Maxolon and Zide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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