Melphalan hydrochloride and Diazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melphalan hydrochloride (melphalan hydrochloride) and Diazepam (diazepam). Common drug interactions include osteomyelitis among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Melphalan hydrochloride and Diazepam. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Melphalan hydrochloride?

Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,970 Melphalan hydrochloride users. Check the latest studies of Melphalan hydrochloride.

What is Diazepam?

Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.

On Jul, 08, 2026

33 people who take Melphalan hydrochloride and Diazepam together, and have interactions are studied.

Melphalan hydrochloride and Diazepam drug interactions.

What are the common drug interactions of Melphalan Hydrochloride and Diazepam, by gender? *:

female:

Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Pneumonia
Swelling
Abdominal pain
Alkalosis
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Atelectasis (partial or complete collapse of the lung)
Blindness

male:

Decreased appetite
Pyrexia (fever)
Lethargy (tiredness)
Neuropathy peripheral (surface nerve damage)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Septic shock (shock due to blood infection)
Somnolence (a state of near-sleep, a strong desire for sleep)
Spinal compression fracture (fracture due to spinal compression on bone)

What are the common drug interactions of Melphalan Hydrochloride and Diazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Anaemia (lack of blood)
Candidiasis (candidiasis or thrush is a fungal infection)
Corynebacterium infection (infection by corynebacterium (diphtheria))
Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
Face oedema (swelling of face)
Febrile infection (infection with temperature rise)
Histiocytosis haematophagic
Hyperammonaemia
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

10-19:

n/a

20-29:

Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Cytomegalovirus test positive
Haematuria (presence of blood in urine)
Interstitial lung disease
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Viral haemorrhagic cystitis (lower urinary tract symptoms that include haematuria and irritative voiding symptoms)
Post transplant lymphoproliferative disorder
Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)

30-39:

n/a

40-49:

Abdominal pain
Abscess (pus)
Alkalosis
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Atelectasis (partial or complete collapse of the lung)
Blindness
Blood albumin decreased
Blood calcium decreased
Blood potassium increased
Carbon dioxide increased

50-59:

Dyspepsia (indigestion)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Exostosis (formation of new bone on the surface of a bone)
Febrile nonhaemolytic transfusion reaction (reaction with fever)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gingival bleeding (bleeding gums)
Gingival disorder (gum disease)
Heart rate increased
Herpes simplex (herpes simplex is a common viral infection)
Hypertension (high blood pressure)

60+:

Pyrexia (fever)
Somnolence (a state of near-sleep, a strong desire for sleep)
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Lethargy (tiredness)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Septic shock (shock due to blood infection)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Androgen deficiency

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 22 people, 66.67%
High Blood Pressure: 8 people, 24.24%
White Blood Cell Count Increased: 4 people, 12.12%
Bone Marrow Conditioning Regimen: 4 people, 12.12%
Csf Leak: 4 people, 12.12%
Hyperventilation: 4 people, 12.12%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 12.12%
Oedema (fluid collection in tissue): 4 people, 12.12%
Oral Candidiasis (fungal infection of mouth): 4 people, 12.12%
Pain: 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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