Melphalan hydrochloride and Medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melphalan hydrochloride (melphalan hydrochloride) and Medrol (methylprednisolone). Common drug interactions include adenomatous polyposis coli among females and myelodysplastic syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Melphalan hydrochloride and Medrol. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Melphalan hydrochloride?

Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,970 Melphalan hydrochloride users. Check the latest studies of Melphalan hydrochloride.

What is Medrol?

Medrol has active ingredients of methylprednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,443 Medrol users. Check the latest studies of Medrol.



On Jul, 08, 2026

18 people who take Melphalan hydrochloride and Medrol together, and have interactions are studied.

Melphalan hydrochloride and Medrol drug interactions.

What are the common drug interactions of Melphalan Hydrochloride and Medrol, by gender? *:

female:

  1. Adenomatous polyposis coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine)
  2. Anaemia (lack of blood)
  3. Antiphospholipid antibodies positive
  4. Anxiety
  5. Aortic valve sclerosis (narrowing of the aortic valve)
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Blood cholesterol increased
  10. Blood immunoglobulin g increased

male:

  1. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  2. Anaemia (lack of blood)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Blood magnesium decreased
  6. Blood sodium decreased
  7. Bone disorder
  8. Bone marrow disorder
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

What are the common drug interactions of Melphalan Hydrochloride and Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Blood magnesium decreased
  4. Blood sodium decreased
  5. Bone disorder
  6. Bone marrow disorder
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  9. Candidiasis (candidiasis or thrush is a fungal infection)
  10. Cardiomyopathy (weakening of the heart muscle)

50-59:

n/a

60+:

  1. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  2. Anaemia (lack of blood)
  3. Abdominal pain upper
  4. Adenomatous polyposis coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine)
  5. Antiphospholipid antibodies positive
  6. Anxiety
  7. Aortic valve sclerosis (narrowing of the aortic valve)
  8. Arthralgia (joint pain)
  9. Asthenia (weakness)
  10. Atelectasis (partial or complete collapse of the lung)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 11 people, 61.11%
  2. Nausea (feeling of having an urge to vomit): 6 people, 33.33%
  3. High Blood Pressure: 6 people, 33.33%
  4. Gout (uric acid crystals building up in the body): 6 people, 33.33%
  5. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 6 people, 33.33%
  6. Constipation: 6 people, 33.33%
  7. Bone Disorder: 6 people, 33.33%
  8. Back Pain: 6 people, 33.33%
  9. Sedation: 4 people, 22.22%
  10. Infection: 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

Do you take Melphalan hydrochloride and Medrol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Melphalan hydrochloride and Medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Melphalan hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melphalan hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Medrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on melphalan hydrochloride and methylprednisolone (the active ingredients of Melphalan hydrochloride and Medrol, respectively), and Melphalan hydrochloride and Medrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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