Sprycel and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sprycel (dasatinib) and Seroquel (quetiapine fumarate). Common drug interactions include blood creatinine increased among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Sprycel and Seroquel. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Sprycel?

Sprycel has active ingredients of dasatinib. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 29,788 Sprycel users. Check the latest studies of Sprycel.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

On Jul, 08, 2026

61 people who take Sprycel and Seroquel together, and have interactions are studied.

What are the common drug interactions of Sprycel and Seroquel, by gender? *:

female:

Blood creatinine increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Eye inflammation
Migraine (headache)
Oedema peripheral (superficial swelling)
Peripheral swelling
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pupil fixed
Renal disorder (kidney disease)
Aggression

male:

Drug ineffective
Fatigue (feeling of tiredness)
Rash
Cardiac disorder
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate antidiuretic hormone secretion
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Sprycel and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Weight increased
Malignant neoplasm progression (cancer tumour came back)
Anaemia (lack of blood)
Blood glucose increased
Decreased appetite
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Gastrointestinal mucosal disorder (disorder of gastrointestinal lining mucous membranes)
Generalised oedema (swelling all over the body)
Neuropathy peripheral (surface nerve damage)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

40-49:

Drug ineffective
Dyspepsia (indigestion)
Gene mutation identification test positive
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nasopharyngitis (inflammation of the nasopharynx)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Pleural effusion (water on the lungs)
Pneumonia
Pneumonia legionella (pneumonia caused by the bacteria legionella)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

Abdominal pain
Constipation
Rash
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate antidiuretic hormone secretion
Pleural effusion (water on the lungs)
Diarrhoea
Eye swelling
Faeces pale
Flushing (the warm, red condition of human skin)

60+:

Drug ineffective
Abnormal sensation in eye
Pulmonary oedema (fluid accumulation in the lungs)
Adverse event
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood calcium increased
Blood potassium increased
Cellulitis (infection under the skin)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 37 people, 60.66%
Depression: 7 people, 11.48%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 6 people, 9.84%
Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 8.20%

* Approximation only. Some reports may have incomplete information.

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