Melphalan hydrochloride and Paxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melphalan hydrochloride (melphalan hydrochloride) and Paxil (paroxetine hydrochloride). Common drug interactions include pain among females and aeromona infection among males.

The phase IV clinical study analyzes what interactions people have when they take Melphalan hydrochloride and Paxil. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Melphalan hydrochloride?

Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,970 Melphalan hydrochloride users. Check the latest studies of Melphalan hydrochloride.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

On Jul, 08, 2026

55 people who take Melphalan hydrochloride and Paxil together, and have interactions are studied.

Melphalan hydrochloride and Paxil drug interactions.

What are the common drug interactions of Melphalan Hydrochloride and Paxil, by gender? *:

female:

Pain
Pain in jaw
Purulent discharge (discharge that contains pus)
Inflammation
Oedema peripheral (superficial swelling)
Osteonecrosis of jaw (death of bone of jaw)
Cardiac failure congestive
Impaired healing
Jaw fracture
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

male:

Aeromona infection (infection caused by bacteria aeromona)
Anaemia (lack of blood)
Cardiac failure congestive
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Chills (felling of cold)
Cholecystitis (infection of gallbladder)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Compression fracture (fracture due to pressure caused by injury)
Conjunctival haemorrhage (bleeding underneath the conjunctiva)

What are the common drug interactions of Melphalan Hydrochloride and Paxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Fluid overload (too much fluid in the blood)
Mucosal inflammation (infection of mucous membrane)
Pyrexia (fever)
Anaemia (lack of blood)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Bone disorder
Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

Osteonecrosis of jaw (death of bone of jaw)
Ejection fraction decreased (systolic heart failure)
Abdominal pain
Abdominal pain upper
Actinomycosis (infection that causes sores, or abscesses)
Anaemia (lack of blood)
Angiopathy (generic term for a disease of the blood vessels)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)

60+:

Asthenia (weakness)
Back pain
Oral pain
Atelectasis (partial or complete collapse of the lung)
Tooth extraction
Fatigue (feeling of tiredness)
Osteomyelitis (infection of bone)
Rib fracture
Actinomycosis (infection that causes sores, or abscesses)
Alopecia (absence of hair from areas of the body)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 52 people, 94.55%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 12 people, 21.82%
Insomnia (sleeplessness): 9 people, 16.36%
High Blood Pressure: 9 people, 16.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 16.36%
Fatigue (feeling of tiredness): 9 people, 16.36%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 8 people, 14.55%

* Approximation only. Some reports may have incomplete information.

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