Mercaptopurine and Vistaril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mercaptopurine (mercaptopurine) and Vistaril (hydroxyzine hydrochloride). Common drug interactions include ovarian cyst among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Mercaptopurine and Vistaril. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

On Jul, 14, 2026

17 people who take Mercaptopurine and Vistaril together, and have interactions are studied.

Mercaptopurine and Vistaril drug interactions.

What are the common drug interactions of Mercaptopurine and Vistaril, by gender? *:

female:

Ovarian cyst (fluid filled sac of the ovary)
Ovarian disorder (disease of ovary)
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pelvic adhesions
Pelvic pain
Pericardial effusion (fluid around the heart)
Peritoneal adhesions
Phonophobia (a morbid fear of sounds including your own voice)
Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)

male:

Abdominal pain
Activated partial thromboplastin time prolonged
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Gamma-glutamyltransferase increased
Glossodynia (a burning or painful sensation in the tongue)
Hepatic steatosis (fatty liver disease)
Malaise (a feeling of general discomfort or uneasiness)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Premature baby
Rectal haemorrhage (bleeding from anus)

What are the common drug interactions of Mercaptopurine and Vistaril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Low birth weight baby
Premature baby

10-19:

Abdominal pain
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Blood bilirubin increased
International normalised ratio increased
Blood alkaline phosphatase increased
Aspartate aminotransferase increased
Febrile neutropenia (fever with reduced white blood cells)
Fatigue (feeling of tiredness)
Gamma-glutamyltransferase increased

20-29:

Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Face injury
Fall

30-39:

n/a

40-49:

Swelling
Tooth erosion (dissolving teeth)
Arthralgia (joint pain)
Abdominal pain upper
Fatigue (feeling of tiredness)
Gait disturbance
Pain
Pain in extremity

50-59:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Aortic valve incompetence
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac disorder
Cardiac failure congestive
Cardiac murmur (an heart sound in valve abnormality)

60+:

Dysphonia (speech disorder attributable to a disorder of phonation)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Glossodynia (a burning or painful sensation in the tongue)
Premature baby
Throat irritation
Tongue blistering

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 8 people, 47.06%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 41.18%
Pain: 7 people, 41.18%
Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord): 4 people, 23.53%
Constipation: 4 people, 23.53%
Fever: 4 people, 23.53%
Headache (pain in head): 2 people, 11.76%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 11.76%
Blood Creatinine Increased: 2 people, 11.76%
Depression: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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