Meropenem and Orgaran drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Meropenem (meropenem) and Orgaran (danaparoid sodium). Common drug interactions include upper respiratory tract inflammation among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Meropenem and Orgaran. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Meropenem?
Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.
What is Orgaran?
Orgaran has active ingredients of danaparoid sodium. eHealthMe is studying from 863 Orgaran users. Check the latest studies of Orgaran.
37 people who take Meropenem and Orgaran together, and have interactions are studied.

What are the common drug interactions of Meropenem and Orgaran, by gender? *:
female:
- Upper respiratory tract inflammation
- Vomiting
- Weight increased
- White blood cell count decreased
- Brain stem haemorrhage (bleeding into structures of brain stem)
- Circulatory collapse
- Fungaemia (fungi circulate in the blood)
- Infection
- Multi-organ failure (multisystem organ failure)
- Renal failure (kidney dysfunction)
male:
- Anaemia (lack of blood)
- Acute respiratory distress syndrome
- Gastric varices
- Haematemesis (vomiting of blood)
- Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
- Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
- Splenic embolism (obstruction in splenic artery)
- Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Renal impairment (severely reduced kidney function)
What are the common drug interactions of Meropenem and Orgaran, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Precursor t-lymphoblastic lymphoma/leukaemia recurrent (precursor b-cell cancer recurrent)
- Acute respiratory distress syndrome
- Anaemia (lack of blood)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Klebsiella infection
- Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
- Subileus
- Thrombocytopenia (decrease of platelets in blood)
- Ascites (accumulation of fluid in the abdominal cavity)
10-19:
- Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation)
- Platelet count decreased
- Pulmonary alveolar haemorrhage (acute bleeding)
- Venoocclusive liver disease (small veins in the liver are obstructed)
- Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hepatic failure (liver failure)
- Immune system disorder
20-29:
- Brain stem haemorrhage (bleeding into structures of brain stem)
- Circulatory collapse
- Fungaemia (fungi circulate in the blood)
- Infection
- Multi-organ failure (multisystem organ failure)
- Renal failure (kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
- Venoocclusive liver disease (small veins in the liver are obstructed)
30-39:
- Anaemia (lack of blood)
- Blood glucose increased
- Decreased appetite
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Gastrointestinal mucosal disorder (disorder of gastrointestinal lining mucous membranes)
- Generalised oedema (swelling all over the body)
- Malignant neoplasm progression (cancer tumour came back)
- Neuropathy peripheral (surface nerve damage)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
40-49:
n/a
50-59:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Anaemia (lack of blood)
- Blood glucose increased
- C-reactive protein increased
- Decreased appetite
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Fungaemia (fungi circulate in the blood)
- Gastrointestinal mucosal disorder (disorder of gastrointestinal lining mucous membranes)
- Generalised oedema (swelling all over the body)
- Neoplasm malignant (cancer tumour)
60+:
- Renal impairment (severely reduced kidney function)
- Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
- Gamma-glutamyltransferase increased
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Transaminases increased
- White blood cell count increased
- Bone marrow failure
- Candida sepsis (candida in blood stream)
- Melaena (the passage of black, tarry stools)
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
What are the existing conditions these people have? *
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 12 people, 32.43%
- Sepsis (a severe blood infection that can lead to organ failure and death): 12 people, 32.43%
- Rickets (softening of bones): 12 people, 32.43%
- Leukoencephalopathy (disease of the white matter in the brain): 11 people, 29.73%
- Pain: 10 people, 27.03%
- Bile Acid Malabsorption: 10 people, 27.03%
- Urinary Tract Infection: 9 people, 24.32%
- Device Related Infection: 9 people, 24.32%
- Insomnia (sleeplessness): 8 people, 21.62%
- Heparin-Induced Thrombocytopenia: 7 people, 18.92%
* Approximation only. Some reports may have incomplete information.
Do you take Meropenem and Orgaran?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Meropenem and Orgaran:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Meropenem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Orgaran:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Meropenem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Orgaran and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on meropenem and danaparoid sodium (the active ingredients of Meropenem and Orgaran, respectively), and Meropenem and Orgaran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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