Piqray and Insomnia exacerbated - a phase IV clinical study of FDA data

Summary:

Insomnia exacerbated is reported as a side effect among people who take Piqray (alpelisib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Kisqali, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Insomnia exacerbated when taking Piqray. It is created by eHealthMe based on reports of 7,290 people who have side effects when taking Piqray from the FDA, and is updated regularly.

What is Piqray?

Piqray has active ingredients of alpelisib. eHealthMe is studying from 7,290 Piqray users. Check the latest studies of Piqray.

What is Insomnia exacerbated?

Insomnia exacerbated (severe sleeplessness) is found to be associated with 2,652 drugs and 974 conditions by eHealthMe. Check the latest studies of Insomnia exacerbated.

On Jul, 14, 2026

7,290 people reported to have side effects when taking Piqray.
Among them, 84 people (1.15%) have Insomnia exacerbated.

Could Piqray cause Insomnia exacerbated?

Among these 84 people:

How long have people been on Piqray when they have Insomnia exacerbated? *

What is the gender of people who have Insomnia exacerbated when taking Piqray? *

female: 100 %
male: 0.0 %

What is the age of people who have Insomnia exacerbated when taking Piqray? *

What are other drugs people take besides Piqray? *

What are other side effects people have besides Insomnia exacerbated? *

Nausea (feeling of having an urge to vomit): 42 people, 50.00%
Diarrhea: 38 people, 45.24%
Fatigue (feeling of tiredness): 37 people, 44.05%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 30 people, 35.71%
Weight Decreased: 29 people, 34.52%
Nausea And Vomiting: 25 people, 29.76%
Rashes (redness): 24 people, 28.57%
Weakness: 22 people, 26.19%
Pain: 20 people, 23.81%
Feeling Abnormal: 19 people, 22.62%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 29 people, 34.52%
Breast Cancer: 28 people, 33.33%
Metastases To Bone (cancer spreads to bone): 5 people, 5.95%
Weight Decreased: 3 people, 3.57%
Sinusitis (inflammation of sinus): 3 people, 3.57%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 3 people, 3.57%
Breast Cancer Female: 3 people, 3.57%
Menopause (end of monthly cycles in women): 2 people, 2.38%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 2 people, 2.38%
Drug Hypersensitivity: 2 people, 2.38%

* Approximation only. Some reports may have incomplete information.

Do you take Piqray and have Insomnia exacerbated?

- Check whether Insomnia exacerbated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Piqray:

Piqray (7,290 reports)

Browse all side effects of Piqray:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia exacerbated:

Insomnia exacerbated (2,652 drugs)

Browse all the conditions that are associated with Insomnia exacerbated:

Insomnia exacerbated (974 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alpelisib (the active ingredients of Piqray) and Piqray (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.