Mestinon and Adalat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mestinon (pyridostigmine bromide) and Adalat (nifedipine). Common drug interactions include blood sodium decreased among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Mestinon and Adalat. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Mestinon?

Mestinon has active ingredients of pyridostigmine bromide. It is often used in myasthenia gravis. eHealthMe is studying from 5,948 Mestinon users. Check the latest studies of Mestinon.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

On Jul, 19, 2026

11 people who take Mestinon and Adalat together, and have interactions are studied.

What are the common drug interactions of Mestinon and Adalat, by gender? *:

female:

Blood sodium decreased
Drug maladministration
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Feeling of body temperature change
Haematuria present (presence of blood in urine due to trauma)
International normalised ratio increased
Joint stiffness
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

male:

Tremor (trembling or shaking movements in one or more parts of your body)
Blood pressure decreased
Iron deficiency anaemia
Nasopharyngitis (inflammation of the nasopharynx)
Pyrexia (fever)
Red blood cell count decreased
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Mestinon and Adalat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Haematocrit decreased
Haemoglobin decreased
Iron deficiency anaemia
Red blood cell count decreased

40-49:

n/a

50-59:

Blood pressure decreased
Blood pressure diastolic increased
Cardiac arrest
Depressed level of consciousness
Dyspnoea (difficult or laboured respiration)
Heart rate increased
Nasopharyngitis (inflammation of the nasopharynx)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Blood sodium decreased
Drug maladministration
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Purpura (purplish discoloration of the skin)
Tremor (trembling or shaking movements in one or more parts of your body)
Abasia (inability to walk)
Abdominal pain upper
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Bone pain
C-reactive protein increased

What are the existing conditions these people have? *

Diabetes: 3 people, 27.27%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 18.18%
Weakness: 1 person, 9.09%
Retinal Haemorrhage (bleeding from retina): 1 person, 9.09%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 9.09%
Iron Deficiency Anaemia: 1 person, 9.09%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Constipation: 1 person, 9.09%
Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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