Metaxalone and Evoxac drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Metaxalone (metaxalone) and Evoxac (cevimeline hydrochloride). Common drug interactions include osteoporosis among females.
The phase IV clinical study analyzes what interactions people have when they take Metaxalone and Evoxac. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Metaxalone?
Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.
What is Evoxac?
Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.
13 people who take Metaxalone and Evoxac together, and have interactions are studied.

What are the common drug interactions of Metaxalone and Evoxac, by gender? *:
female:
- Osteoporosis (bones weak and more likely to break)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haematoma (collection of blood outside the blood vessels)
- Hypermobility syndrome (abnormalities cause abnormal stress on a joint or many joint)
- Impaired gastric emptying
- Memory impairment
- Nephrolithiasis (calculi in the kidneys)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Therapeutic response unexpected
male:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 100.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 53.85%
- Pain: 1 person, 7.69%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Metaxalone and Evoxac?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Metaxalone (4,452 reports)
- Evoxac (2,028 reports)
Browse all drug interactions of Metaxalone and Evoxac:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Metaxalone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Evoxac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metaxalone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Evoxac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metaxalone and cevimeline hydrochloride (the active ingredients of Metaxalone and Evoxac, respectively), and Metaxalone and Evoxac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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