Metformin and Desferal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Desferal (deferoxamine mesylate). Common drug interactions include vomiting among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Metformin and Desferal. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Metformin?
Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.
What is Desferal?
Desferal has active ingredients of deferoxamine mesylate. It is often used in iron overload. eHealthMe is studying from 2,248 Desferal users. Check the latest studies of Desferal.
31 people who take Metformin and Desferal together, and have interactions are studied.

What are the common drug interactions of Metformin and Desferal, by gender? *:
female:
- Vomiting
- Diarrhoea
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Nausea (feeling of having an urge to vomit)
- Haemolytic anaemia (anaemia due to haemolysis)
- Asthenia (weakness)
- Decreased appetite
- Diabetes mellitus inadequate control
- General physical health deterioration (weak health status)
- Insomnia (sleeplessness)
male:
- Pyrexia (fever)
- Blood creatinine increased
- Aphthous stomatitis (mouth ulcer)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Cellulitis (infection under the skin)
- Erythema (redness of the skin)
- Gout (uric acid crystals building up in the body)
- Inflammation
- Inflammatory marker increased
What are the common drug interactions of Metformin and Desferal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Liver disorder (liver diseases)
20-29:
- Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
30-39:
- Cough
40-49:
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Diabetes mellitus inadequate control
- Weight increased
50-59:
- Renal impairment (severely reduced kidney function)
- Blood creatinine increased
- Blood urea increased
- Diarrhoea
- Stomatitis (inflammation of mucous membrane of mouth)
- Abscess jaw (tooth abscess or root abscess)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Subcutaneous abscess
- Alanine aminotransferase increased
- Aphthous stomatitis (mouth ulcer)
60+:
- Diarrhoea
- Vomiting
- Pyrexia (fever)
- Asthenia (weakness)
- Decreased appetite
- General physical health deterioration (weak health status)
- Insomnia (sleeplessness)
- Pneumonia
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Fall
What are the existing conditions these people have? *
- Type 2 Diabetes: 5 people, 16.13%
- Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 16.13%
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 3 people, 9.68%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 9.68%
- High Blood Pressure: 3 people, 9.68%
- High Blood Cholesterol: 3 people, 9.68%
- Chronic Kidney Disease: 3 people, 9.68%
- Rickets (softening of bones): 2 people, 6.45%
- Fever: 2 people, 6.45%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 6.45%
* Approximation only. Some reports may have incomplete information.
Do you take Metformin and Desferal?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Metformin and Desferal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Metformin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Desferal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metformin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Desferal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on metformin hydrochloride and deferoxamine mesylate (the active ingredients of Metformin and Desferal, respectively), and Metformin and Desferal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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