Metformin and Octreotide acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Octreotide acetate (octreotide acetate). Common drug interactions include back pain among females and blood pressure systolic increased among males.

The phase IV clinical study analyzes what interactions people have when they take Metformin and Octreotide acetate. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Octreotide acetate?

Octreotide acetate has active ingredients of octreotide acetate. eHealthMe is studying from 2,449 Octreotide acetate users. Check the latest studies of Octreotide acetate.

On Jun, 10, 2026

85 people who take Metformin and Octreotide acetate together, and have interactions are studied.

Metformin and Octreotide acetate drug interactions.

What are the common drug interactions of Metformin and Octreotide Acetate, by gender? *:

female:

Back pain
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Blood glucose increased
Blood pressure decreased
Drug ineffective
Heart rate decreased
Pyrexia (fever)
Arthralgia (joint pain)

male:

Blood pressure systolic increased
Diarrhoea
Haemoglobin decreased
Pulmonary mass
Tooth abscess (pus formation in tooth)
Tooth infection
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
Abdominal distension
Asthenia (weakness)
Epistaxis (bleed from the nose)

What are the common drug interactions of Metformin and Octreotide Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Haematocrit decreased
Haemoglobin decreased
Red cell distribution width increased
Addison's disease (addison's disease, a hormonal disorder disease)

40-49:

Hyperglycaemia (high blood sugar)
Arthralgia (joint pain)
Blood triglycerides increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Cyst (a closed sac)
Diarrhoea
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dry eye (lack of adequate tears)
Dry skin
Emotional distress

50-59:

Pain in extremity
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Weight decreased
Abnormal faeces (abnormal stool)
Anal abscess
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Blood magnesium decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chills (felling of cold)

60+:

Fatigue (feeling of tiredness)
Diarrhoea
Heart rate decreased
Blood glucose increased
Erythema (redness of the skin)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Asthenia (weakness)
Fall
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 14 people, 16.47%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 12 people, 14.12%
Carcinoid Tumor: 9 people, 10.59%
Type 2 Diabetes: 7 people, 8.24%
Neuroendocrine Tumor: 7 people, 8.24%
Diarrhea: 7 people, 8.24%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 7.06%
Pain: 6 people, 7.06%
High Blood Pressure: 6 people, 7.06%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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