Methadone hydrochloride and Senna alexandrina drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methadone hydrochloride (methadone hydrochloride) and Senna alexandrina (senna). Common drug interactions include back pain among females and adverse event among males.

The phase IV clinical study analyzes what interactions people have when they take Methadone hydrochloride and Senna alexandrina. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Methadone hydrochloride?

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 8,598 Methadone hydrochloride users. Check the latest studies of Methadone hydrochloride.

What is Senna alexandrina?

Senna alexandrina has active ingredients of senna. eHealthMe is studying from 2,853 Senna alexandrina users. Check the latest studies of Senna alexandrina.

On Jul, 14, 2026

11 people who take Methadone hydrochloride and Senna alexandrina together, and have interactions are studied.

Methadone hydrochloride and Senna alexandrina drug interactions.

What are the common drug interactions of Methadone Hydrochloride and Senna Alexandrina, by gender? *:

female:

Back pain
Dysphagia (a condition in which swallowing is difficult or painful)
Nausea (feeling of having an urge to vomit)

male:

Adverse event
Back pain
Blood urea increased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Crepitations (noises are produced by the rubbing of parts one against the other)
Dysstasia (difficulty in standing)
Dysuria (painful or difficult urination)
Fluid overload (too much fluid in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Micturition urgency (urgency to pass the urine)

What are the common drug interactions of Methadone Hydrochloride and Senna Alexandrina, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood potassium increased
Dysstasia (difficulty in standing)
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

Back pain
Adverse event
Blood pressure decreased
Infusion related reaction
Petechiae (a small red or purple spot caused by bleeding into the skin)
Dysphagia (a condition in which swallowing is difficult or painful)
Nausea (feeling of having an urge to vomit)

60+:

Pulmonary embolism (blockage of the main artery of the lung)
Arthralgia (joint pain)
Micturition urgency (urgency to pass the urine)
Pleural effusion (water on the lungs)
Pneumonia
Pulmonary congestion (congestion in the lungs)
Pulmonary mass
Skin wound
Urinary retention (the inability to completely or partially empty the bladder)
Urine output decreased

What are the existing conditions these people have? *

Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 6 people, 54.55%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 2 people, 18.18%
Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 9.09%
Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 9.09%
Pneumonia: 1 person, 9.09%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 9.09%
Lower Urinary Tract Symptoms: 1 person, 9.09%
Hyperkalemia (damage to or disease of the kidney): 1 person, 9.09%
Gout (uric acid crystals building up in the body): 1 person, 9.09%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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