Methimazole and Diazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Methimazole (methimazole) and Diazepam (diazepam). Common drug interactions include diaphragmatic disorder among females and akathisia among males.
The phase IV clinical study analyzes what interactions people have when they take Methimazole and Diazepam. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.
What is Methimazole?
Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.
What is Diazepam?
Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.
81 people who take Methimazole and Diazepam together, and have interactions are studied.

What are the common drug interactions of Methimazole and Diazepam, by gender? *:
female:
- Diaphragmatic disorder
- Diaphragmatic paralysis (acquired dysfunction of the phrenic nerve)
- Difficulty in walking
- Disturbance in attention
- Drug administration error
- Drug dependence
- Drug toxicity
- Ear infection
- Eye pain
- Fall
male:
- Akathisia (a movement disorder characterized by a feeling of inner restlessness)
- Cardiac failure
- Abdominal pain
- Eating disorder
- General physical health deterioration (weak health status)
- Nausea (feeling of having an urge to vomit)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Vomiting
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Emotional distress
What are the common drug interactions of Methimazole and Diazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Pulmonary embolism (blockage of the main artery of the lung)
- Limb injury
- Localised infection (infection at the single location)
- Pelvic pain
- Skin discolouration (change of skin colour)
- Vulvovaginal pain
- Drug ineffective
40-49:
- Depression
- Fear
- Food craving
- Increased appetite
- Micturition disorder (disease of passing urine)
- Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Suicidal ideation
- Circulatory collapse
- Back disorder
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Bone density decreased
- Chronic kidney disease
- Death
- Emotional distress
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Decreased appetite
60+:
- Chronic kidney disease
- Axonal neuropathy (dysfunction of axon nerves)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Cardiac failure
- Emotional distress
- Encephalitis (inflammation of the brain)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Limb discomfort (discomfort in leg)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
What are the existing conditions these people have? *
- Pain: 11 people, 13.58%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 12.35%
- High Blood Pressure: 10 people, 12.35%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 11.11%
- Depression: 9 people, 11.11%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 9.88%
- Diabetes: 7 people, 8.64%
- Sleep Disorder: 6 people, 7.41%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 7.41%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 7.41%
* Approximation only. Some reports may have incomplete information.
Do you take Methimazole and Diazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Methimazole (8,016 reports)
- Diazepam (108,384 reports)
Browse all drug interactions of Methimazole and Diazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Methimazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methimazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on methimazole and diazepam (the active ingredients of Methimazole and Diazepam, respectively), and Methimazole and Diazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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