Methylprednisolone and Linagliptin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylprednisolone (methylprednisolone) and Linagliptin (linagliptin). Common drug interactions include gout among females and nephritis among males.

The phase IV clinical study analyzes what interactions people have when they take Methylprednisolone and Linagliptin. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Methylprednisolone?

Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.

What is Linagliptin?

Linagliptin has active ingredients of linagliptin. eHealthMe is studying from 8,112 Linagliptin users. Check the latest studies of Linagliptin.



On Jul, 10, 2026

39 people who take Methylprednisolone and Linagliptin together, and have interactions are studied.

Methylprednisolone and Linagliptin drug interactions.

What are the common drug interactions of Methylprednisolone and Linagliptin, by gender? *:

female:

  1. Gout (uric acid crystals building up in the body)
  2. Headache (pain in head)
  3. Hypertension (high blood pressure)
  4. Insomnia (sleeplessness)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Metastases to liver (cancer spreads to liver)
  7. Myalgia (muscle pain)
  8. Nausea (feeling of having an urge to vomit)
  9. Osteoporosis (bones weak and more likely to break)
  10. Pain in extremity

male:

  1. Nephritis (inflammation of the nephrons in the kidneys)
  2. Constipation
  3. Folliculitis (infection of hair root)
  4. Herpes simplex (herpes simplex is a common viral infection)
  5. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  6. Oral candidiasis (fungal infection of mouth)
  7. Oral herpes (viral infection of mouth)
  8. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  9. Thrombocytopenia (decrease of platelets in blood)
  10. White blood cell count decreased

What are the common drug interactions of Methylprednisolone and Linagliptin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood creatinine increased
  2. Kidney transplant rejection
  3. Pneumonia
  4. Pyrexia (fever)
  5. Respiratory tract infection

50-59:

  1. Nephritis (inflammation of the nephrons in the kidneys)
  2. Abdominal pain
  3. Chorioretinopathy (collection of fluid under the retina that results in visual distortion)
  4. Cytomegalovirus infection
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

  1. Constipation
  2. Blood creatinine increased
  3. Glomerular filtration rate decreased
  4. Glycosylated haemoglobin increased
  5. Hepatic failure (liver failure)
  6. Intervertebral disc protrusion (spinal disc protrusion)
  7. Leukopenia (less number of white blood cells in blood)
  8. Malignant neoplasm progression (cancer tumour came back)
  9. Menopausal symptoms
  10. Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the existing conditions these people have? *

  1. High Blood Pressure: 13 people, 33.33%
  2. Diabetes: 12 people, 30.77%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 17.95%
  4. High Blood Cholesterol: 5 people, 12.82%
  5. Rashes (redness): 5 people, 12.82%
  6. Diarrhea: 5 people, 12.82%
  7. Vasculitis (inflammation of a blood vessel or blood vessels): 4 people, 10.26%
  8. Gout (uric acid crystals building up in the body): 4 people, 10.26%
  9. Constipation: 4 people, 10.26%
  10. Insomnia (sleeplessness): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Methylprednisolone and Linagliptin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Methylprednisolone and Linagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylprednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Linagliptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methylprednisolone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Linagliptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone and linagliptin (the active ingredients of Methylprednisolone and Linagliptin, respectively), and Methylprednisolone and Linagliptin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: