Mevacor and Ibuprofen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Mevacor (lovastatin) and Ibuprofen (ibuprofen). Common drug interactions include chronic kidney disease among females and hypophagia among males.
The phase IV clinical study analyzes what interactions people have when they take Mevacor and Ibuprofen. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.
What is Mevacor?
Mevacor has active ingredients of lovastatin. It is often used in high blood cholesterol. eHealthMe is studying from 4,988 Mevacor users. Check the latest studies of Mevacor.
What is Ibuprofen?
Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.
84 people who take Mevacor and Ibuprofen together, and have interactions are studied.

What are the common drug interactions of Mevacor and Ibuprofen, by gender? *:
female:
- Chronic kidney disease
- Drug hypersensitivity
- Obesity (having too much body fat)
- Depression
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
- Hypertriglyceridaemia (excess of triglycerides in the blood)
- Nausea (feeling of having an urge to vomit)
- Renal injury (kidney injury)
- Vomiting
male:
- Hypophagia (reduced food intake)
- Anxiety
- Cerebral arteriosclerosis (thickening and hardening of the walls of the arteries in the brain)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Decreased interest
- Deformity (disfigurement)
- Depression
- Emotional distress
- General physical health deterioration (weak health status)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
What are the common drug interactions of Mevacor and Ibuprofen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetes mellitus inadequate control
- Hyperglycaemia (high blood sugar)
- Obesity (having too much body fat)
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
30-39:
- Colon cancer metastatic (cancer of colon spreads to other part of body)
- Fatigue (feeling of tiredness)
- Hypersensitivity
- Hypersomnia (excessive daytime sleepiness (eds))
- Myalgia (muscle pain)
40-49:
- Anxiety
- Emotional distress
- General physical health deterioration (weak health status)
- Injury
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Pulmonary embolism (blockage of the main artery of the lung)
- Quality of life decreased
- Agitation (state of anxiety or nervous excitement)
- Atelectasis (partial or complete collapse of the lung)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
50-59:
- Blood alkaline phosphatase nos increased
- Blood bilirubin increased
- Cardiac failure congestive
- Depression
- Drug hypersensitivity
- Dyspepsia (indigestion)
- Emotional distress
- Hypokalaemia (low potassium)
- Jugular vein thrombosis (clot in jugular vein)
- Myalgia (muscle pain)
60+:
- Anxiety
- Hypophagia (reduced food intake)
- Body height decreased
- Bone disorder
- Cellulitis (infection under the skin)
- Cerebral arteriosclerosis (thickening and hardening of the walls of the arteries in the brain)
- Decreased interest
- Deformity (disfigurement)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
What are the existing conditions these people have? *
- High Blood Pressure: 15 people, 17.86%
- Stress And Anxiety: 14 people, 16.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 16.67%
- Osteoporosis (bones weak and more likely to break): 12 people, 14.29%
- Depression: 8 people, 9.52%
- Renal Disorder (kidney disease): 6 people, 7.14%
- Gout (uric acid crystals building up in the body): 6 people, 7.14%
- Gastric Ulcer (stomach ulcer): 6 people, 7.14%
- Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 7.14%
- Anaemia (lack of blood): 6 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Mevacor and Ibuprofen?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Mevacor and Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Mevacor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mevacor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibuprofen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on lovastatin and ibuprofen (the active ingredients of Mevacor and Ibuprofen, respectively), and Mevacor and Ibuprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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