Midodrine hydrochloride and Droxidopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Midodrine hydrochloride (midodrine hydrochloride) and Droxidopa (droxidopa). Common drug interactions include asphyxia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Midodrine hydrochloride and Droxidopa. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Midodrine hydrochloride?

Midodrine hydrochloride has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 3,274 Midodrine hydrochloride users. Check the latest studies of Midodrine hydrochloride.

What is Droxidopa?

Droxidopa has active ingredients of droxidopa. eHealthMe is studying from 1,093 Droxidopa users. Check the latest studies of Droxidopa.

On Jul, 16, 2026

82 people who take Midodrine hydrochloride and Droxidopa together, and have interactions are studied.

Midodrine hydrochloride and Droxidopa drug interactions.

What are the common drug interactions of Midodrine Hydrochloride and Droxidopa, by gender? *:

female:

Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dizziness
Dry skin
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypokalaemia (low potassium)
Hypokinesia (decreased bodily movement)
Muscular weakness (muscle weakness)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)

male:

Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)
Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Asthenia (weakness)
Cardiac arrest
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Arrhythmia (irregular heartbeat)
Blood creatinine increased

What are the common drug interactions of Midodrine Hydrochloride and Droxidopa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Burning sensation
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Vomiting
Skin exfoliation (removal of the oldest dead skin cells)

30-39:

n/a

40-49:

n/a

50-59:

Hypokinesia (decreased bodily movement)
Loss of consciousness
Wound infection

60+:

Dyskinesia (abnormality or impairment of voluntary movement)
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Abdominal pain
Cough
Insomnia (sleeplessness)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Aggression
Cardiac failure acute
Device dislocation
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Parkinson's Disease: 38 people, 46.34%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 9 people, 10.98%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 8 people, 9.76%
Insomnia (sleeplessness): 7 people, 8.54%
Hallucinations (sensations that appear real but are created by your mind): 6 people, 7.32%
Nausea And Vomiting: 5 people, 6.10%
Nausea (feeling of having an urge to vomit): 5 people, 6.10%
Abdominal Distension: 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

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