Minoxidil and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minoxidil (minoxidil) and Rapamune (sirolimus). Common drug interactions include pyrexia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Minoxidil and Rapamune. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Minoxidil?

Minoxidil has active ingredients of minoxidil. It is often used in hair loss. eHealthMe is studying from 29,925 Minoxidil users. Check the latest studies of Minoxidil.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

On Jul, 20, 2026

69 people who take Minoxidil and Rapamune together, and have interactions are studied.

Minoxidil and Rapamune drug interactions.

What are the common drug interactions of Minoxidil and Rapamune, by gender? *:

female:

Pyrexia (fever)
Dry gangrene (diminished blood supply due to vascular problems)
Endometrial hyperplasia (enlargement of uterus wall)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Ovarian cyst (fluid filled sac of the ovary)
Pancreatitis (inflammation of pancreas)
Pericardial effusion (fluid around the heart)
Abdominal pain
Aortic disorder
Blood sodium decreased

male:

Pyrexia (fever)
Blood creatinine increased
Fluid overload (too much fluid in the blood)
Sepsis (a severe blood infection that can lead to organ failure and death)
Chills (felling of cold)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Diarrhoea
Drug hypersensitivity
Graft dysfunction
Haematocrit decreased

What are the common drug interactions of Minoxidil and Rapamune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Disease recurrence
Dehydration (dryness resulting from the removal of water)
Nausea (feeling of having an urge to vomit)
Oral intake reduced
Respiratory rate increased (excess breathing rate/min)
Upper respiratory tract infection
Viral infection
Vomiting

10-19:

Graft dysfunction
Blood creatine phosphokinase increased
Blood creatinine increased
Blood glucose increased
Blood potassium increased
Complications of transplanted kidney
Dehydration (dryness resulting from the removal of water)
Lipase increased
Renal impairment (severely reduced kidney function)

20-29:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Drug level decreased
Haematocrit decreased
Haemoglobin decreased
Renal failure acute (rapid kidney dysfunction)
Decreased appetite
Hyperglycaemia (high blood sugar)
Kidney transplant rejection
Malaise (a feeling of general discomfort or uneasiness)
Productive cough

30-39:

Haemoglobin decreased
Blood creatinine increased
Endometrial hyperplasia (enlargement of uterus wall)
Haematocrit decreased
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Ovarian cyst (fluid filled sac of the ovary)
Abdominal pain
Blood pressure systolic increased
Haemorrhage (bleeding)
Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)

40-49:

Pyrexia (fever)
Blood creatinine increased
Drug hypersensitivity
Kidney transplant rejection
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Abdominal pain
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Haemoglobin decreased
Myositis (inflammation of the muscles)

50-59:

Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Kidney transplant rejection
Loss of consciousness
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Platelet count decreased
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Respiratory disorder (respiratory disease)
Skin exfoliation (removal of the oldest dead skin cells)

60+:

Haemoglobin decreased
Cardiac failure congestive
Pulmonary oedema (fluid accumulation in the lungs)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal tenderness
Acute respiratory distress syndrome
Anuria (failure of the kidneys to produce urine)
Aortic calcification (aortic calcification sign of heart valve disease)
Aortic valve incompetence

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 17.39%
High Blood Cholesterol: 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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