Misoprostol and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Misoprostol (misoprostol) and Melatonin (melatonin). Common drug interactions include dry eye among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Misoprostol and Melatonin. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Misoprostol?

Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 8,222 Misoprostol users. Check the latest studies of Misoprostol.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

On Jul, 20, 2026

56 people who take Misoprostol and Melatonin together, and have interactions are studied.

Misoprostol and Melatonin drug interactions.

What are the common drug interactions of Misoprostol and Melatonin, by gender? *:

female:

Dry eye (lack of adequate tears)
Escherichia sepsis (bacterial infection by escherichia coli)
Eye pain
Groin abscess (pus in groin)
Headache (pain in head)
Heart rate increased
Herpes zoster
Hot flush (sudden feelings of heat)
Infusion related reaction
Infusion site bruising

male:

Headache (pain in head)
Pneumonia
Pyrexia (fever)
Suicidal ideation
Wound
Contusion (a type of hematoma of tissue in which capillaries)
Joint injury
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Blood pressure increased
Brain injury

What are the common drug interactions of Misoprostol and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nerve injury
Neuritis (inflammation of nerve)
Restless legs syndrome (a powerful urge to move your legs)

30-39:

Alopecia (absence of hair from areas of the body)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nausea (feeling of having an urge to vomit)

40-49:

Subcutaneous abscess
Abscess (pus)
Abscess limb (limb infection)
Ankle fracture
Cellulitis (infection under the skin)
Escherichia sepsis (bacterial infection by escherichia coli)
Fall
Fatigue (feeling of tiredness)
Groin abscess (pus in groin)
Headache (pain in head)

50-59:

Road traffic accident
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Snoring
Spinal disorder (disease of spine a back bone)
Weight increased
Arrhythmia (irregular heartbeat)
Back pain
Oropharyngeal spasm (contraction of oropharynx)
Sedation
Dry throat

60+:

Asthenia (weakness)
Back pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abasia (inability to walk)
Ataxia (loss of full control of bodily movements)
Confusional state
Constipation
Depression
Dizziness
Dry eye (lack of adequate tears)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 16 people, 28.57%
Pain: 12 people, 21.43%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 14.29%
Combined Immunodeficiency: 6 people, 10.71%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 7.14%
Gait Disturbance: 4 people, 7.14%
Type 2 Diabetes: 3 people, 5.36%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 3 people, 5.36%
Primary Immunodeficiency Syndrome: 3 people, 5.36%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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