Misoprostol and Melatonin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Misoprostol and Melatonin. Common interactions include necrotising fasciitis among females and headache among males.
The phase IV clinical study analyzes what interactions people who take Misoprostol and Melatonin have. It is created by eHealthMe based on reports of 44 people who take Misoprostol and Melatonin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
44 people who take Misoprostol and Melatonin together, and have interactions are studied.
What is Misoprostol?
Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 7,628 Misoprostol users for its effectiveness, alternative drugs and more.
What is Melatonin?
Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 43,018 Melatonin users for its effectiveness, alternative drugs and more.
Number of Misoprostol and Melatonin reports submitted per year:

Common Misoprostol and Melatonin drug interactions by gender *:
female:
- Necrotising fasciitis
- Ocular discomfort
- Palpitations
- Perineal abscess
- Perirectal abscess
- Sepsis
- Tooth abscess
- Urinary tract infection
- Vulval abscess
- Abdominal discomfort
male:
- Headache
- Depression
- Blood pressure increased
- Diarrhoea
- Hypermetabolism
- Migraine
- Pain
- Pneumonia aspiration
- Snoring
- Brain injury
Common Misoprostol and Melatonin drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Nerve injury
- Neuritis
- Restless legs syndrome
30-39:
- Alopecia
- Multiple sclerosis
- Multiple sclerosis relapse
- Nausea
40-49:
- Subcutaneous abscess
- Abscess
- Abscess limb
- Cellulitis
- Escherichia sepsis
- Groin abscess
- Necrotising fasciitis
- Perineal abscess
- Perirectal abscess
- Sepsis
50-59:
- Oesophageal spasm
- Presyncope
- Weight decreased
- Dysgeusia
- Postmenopausal haemorrhage
- Pyrexia
- Syncope
- Tongue coated
- White blood cell count decreased
- Headache
60+:
- Diarrhoea
- Asthenia
- Dizziness
- Dry eye
- Eye pain
- Fall
- Gait disturbance
- Head injury
- Heart rate increased
- Hot flush
Common conditions people have *:
- Immunodeficiency Common Variable: 10 people, 22.73%
- Pain: 9 people, 20.45%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 18.18%
- Combined Immunodeficiency: 5 people, 11.36%
- Gait Disturbance: 4 people, 9.09%
- Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 3 people, 6.82%
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 6.82%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Misoprostol and Melatonin?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Misoprostol (7,628 reports)
- Melatonin (43,018 reports)
Browse all drug interactions of Misoprostol and Melatonin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Misoprostol side effects:
- Pain: 553 reports
- Birth control: 503 reports
- Fever: 401 reports
- Muscle spasms (muscle contraction): 360 reports
- Drug ineffective: 358 reports
- Dizziness: 357 reports
Browse all side effects of Misoprostol:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Melatonin side effects:
- Fatigue (feeling of tiredness): 3,807 reports
- Headache (pain in head): 2,371 reports
- Drug ineffective: 2,366 reports
- Diarrhea: 2,362 reports
- Insomnia (sleeplessness): 2,236 reports
- Pain: 2,058 reports
- Weakness: 2,031 reports
- Dizziness: 2,016 reports
- Stress and anxiety: 2,002 reports
Browse all side effects of Melatonin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Misoprostol interactions:
- Misoprostol and Mifepristone: 1,573 reports
- Misoprostol and Doxycycline: 1,369 reports
- Misoprostol and Methotrexate: 768 reports
- Misoprostol and Prednisone: 660 reports
- Misoprostol and Enbrel: 518 reports
- Misoprostol and Diclofenac sodium: 387 reports
- Misoprostol and Humira: 355 reports
- Misoprostol and Omeprazole: 308 reports
- Misoprostol and Tramadol: 301 reports
- Misoprostol and Folic acid: 291 reports
Browse all interactions between Misoprostol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Melatonin interactions:
- Melatonin and Vitamin d: 7,492 reports
- Melatonin and Aspirin: 6,947 reports
- Melatonin and Gabapentin: 5,770 reports
- Melatonin and Omeprazole: 4,872 reports
- Melatonin and Vitamin d3: 4,597 reports
- Melatonin and Tylenol: 3,792 reports
- Melatonin and Prednisone: 3,753 reports
- Melatonin and Magnesium: 3,650 reports
- Melatonin and Vitamin b12: 3,496 reports
- Melatonin and Fish oil: 3,484 reports
Browse all interactions between Melatonin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on misoprostol and melatonin (the active ingredients of Misoprostol and Melatonin, respectively), and Misoprostol and Melatonin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Misoprostol and Melatonin.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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